Gout Arthritis, Knee Arthritis, Microcrystal Disease, Osteoarthritis, Knee
Conditions
Brief summary
The research study aims to evaluate the synovial fluid to highlight the presence of possible micropolymers (micro/nanoplastics) in order to better understand the pathophysiology of joint degenerative processes. For patients with liquid under tension at the joint level, the symptomatology often requires evacuation by puncture under ultrasound guidance. The intervention will be performed only for patients for whom this therapeutic indication exists anyway by their physician. The investigators want to use this liquid for Microscopic and Spectrophotometric evaluation.
Interventions
DIAGNOSTIC_TESTSynovial fluid analysis
For patients with knee under tension at the joint level, the symptomatology often requires evacuation by puncture under ultrasound guidance. The intervention will be performed only for patients for whom this therapeutic indication exists anyway by their physicians. After making the evacuation we will want to use this liquid for Microscopic and Spectrophotometric evaluation
Sponsors
Iuliu Hatieganu University of Medicine and Pharmacy
Study design
Observational model
COHORT
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to 90 Years
Healthy volunteers
No
Inclusion criteria
* arthritis of the knee with liquid aspiration recommendation * age \>18 years
Exclusion criteria
--refusal of the patient to participate -age\<18 years
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| microplastics | immediately after liquid extraction | evaluation with spectrophotometry and optic microscopy |
| nanoplastics | immediately after liquid extraction | evaluation with spectrophotometry and optic microscopy |
Outcome results
None listed