Opioid Dependence, Overdose
Conditions
Keywords
opioid dependence, opioid maintenance treatment, methadone, buprenorphine
Brief summary
Opioid dependence, for example involving addiction to injected or inhaled heroin or similar compounds, is associated with high mortality, typically from opioid overdose, and causes major physical and mental health complications, social problems and crime. Opioid maintenance treatment (OMT) has proven effective in opioid dependence. In 2014, a patient's choice reform in Skåne county, Sweden, was introduced and led to a vast extension of OMT in the region, including a large number of treatment providers and high access to treatment. Still, opioid-related mortality in the region remains high. While patients' access to treatment has been increased, the content and nature of treatment in the present system has been questioned. The present system, which dramatically altered treatment conditions and access for OMT in this region, has never been formally evaluated in any large-scale study. This study aims to assess clinical course of patients receiving OMT before and during the patient choice reform system, and effects on the extent and nature of opioid-related mortality in the region.
Interventions
DRUGOpioid maintenance treatment
A reform dramatically expanding access to opioid maintenance treatment (with methadone or buprenorphine) in the region.
Sponsors
Lund University
Region Skane
Study design
Observational model
ECOLOGIC_OR_COMMUNITY
Time perspective
RETROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* Patients included in opioid maintenance treatment in Skåne region.
Exclusion criteria
* None.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Mortality | study inclusion through 2022 | Mortality and cause of death |
| Hospitalization for substance use disorder treatment | study inclusion through 2022 | Hospitalization for substance use disorder treatment |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Mental health disorder | study inclusion through 2022 | Occurrence of a mental health disorder diagnosis aparts from opioid dependence in diagnosis and prescription drug registers |
| Physical disorder | study inclusion through 2022 | Occurrence of a physical disorder diagnosis aparts from opioid dependence in diagnosis and prescription drug registers |
Countries
Sweden
Contacts
Primary ContactAnders Håkansson, PhD
Outcome results
None listed