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Determination of the Red Cell Distribution Width, NT-proBNP and cTnT in Acute Myocardial Infarction Patients

Determination of the Relationship Between Red Cell Distribution Width, NT-proBNP and cTnT in Acute Myocardial Infarction Patients

Status
UNKNOWN
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT05677503
Enrollment
30
Registered
2023-01-10
Start date
2023-01-15
Completion date
2023-07-30
Last updated
2023-01-12

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Myocardial Infarction

Brief summary

the study is to investigate the relationship of several parameters of complete blood count (CBC) including RDW with N-terminal pro-B-type natriuretic peptide (NT-proBNP) and cardiac troponin T (cTnT) in a cohort of acute myocardial infarction (AMI) patients.

Detailed description

Patients and methods: * Type of study: Observational prospective study * Place of study: Sohag cardiology and gastroenterology center, department of cardiology and cardiac care unit. * Ethical considerations: This research will be revised by the Scientific Ethical Committee of Sohag University Hospital. Consents will be taken from all patients. * Study Methods: * A prospective study on 30 patients diagnosed as acute myocardial infarction on which measurement of CBC, serum NT-proBNP, and cTnT levels will be performed at the time of admission and by the time of discharge. 1. Full history: 1. Personal history: e.g. age, sex and smoking. 2. Family history of cardiac diseases 3. Medical history of: Hypertension, Ischemic heart disease, prior coronary artery bypass grafting, Prior Percutaneous coronary intervention, Prior Stroke, Prior Atrial fibrillation, therapeutic history 2. Detailed clinical examination 3. Electrocardiogram 4. Laboratory investigation: 1. Routine investigation in the form of CBC including RDW 2. Specific investigation which include NT-proBNP and cTnT

Interventions

DIAGNOSTIC_TESTCBC

measurement of CBC will be performed at the time of admission and by the time of discharge

DIAGNOSTIC_TEST(NT-proBNP)

measurement of serum NT-proBNP levels will be performed at the time of admission and by the time of discharge

DIAGNOSTIC_TEST(cTnT)

measurement of cTnT levels will be performed at the time of admission and by the time of discharge

Sponsors

Sohag University
Lead SponsorOTHER

Study design

Observational model
CASE_ONLY
Time perspective
PROSPECTIVE

Eligibility

Sex/Gender
ALL
Age
18 Years to 80 Years
Healthy volunteers
No

Inclusion criteria

* patients diagnosed as acute myocardial infarction

Exclusion criteria

Patient with * Decompensated heart failure * Pulmonary hypertention * Acute pulmonary embolism * Septic shock

Design outcomes

Primary

MeasureTime frameDescription
complete blood count (CBC)7 monthsmeasurement of CBC levels will be performed
Level of (NT-proBNP)7 monthsmeasurement of serum NT-proBNP level will be performed
Level of (cTnT)7 monthsmeasurement of cTnT level will be performed

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026