Human Papilloma Virus (HPV) Vaccine
Conditions
Keywords
Human Papillomavirus, Vaccination, Multi-level intervention, Community Health Centers, Behavioral
Brief summary
This intervention study will use parent-, provider-, and health center-level strategies to promote HPV vaccination among 11-17 year olds receiving care in 8 community health centers in Florida, will explore factors related to the intervention effect, and will explore implementation outcomes of the intervention.
Detailed description
The goals of this multi-level intervention study are to: 1) test whether HPV MISTICS intervention increases human papillomavirus (HPV) vaccine initiation and completion rates among 11-17-year-old adolescents in 8 Health Choice Network-affiliated community health centers in Florida. 2) Explore other factors related to the intervention effect. 3) Explore implementation outcomes (i.e., reach, adoption, implementation, maintenance, and sustainability) and identify implementation barriers and facilitators with a focus on equity. The study will use parent-, provider-, and health center-level strategies to promote HPV vaccination.
Interventions
BEHAVIORALHPV MISTICS -Provider Level
The HPV MISTICS (Multilevel Intervention Strategies Targeting Immunization in Community Settings) provider-level intervention for all clinical staff (e.g., physicians, nurses, medical assistants) includes a 1-hour online training session on the Announcement Approach (i.e., presumptive recommendation) to recommend adolescent vaccinations.
BEHAVIORALHPV MISTICS - Parent Level
The HPV MISTICS (Multilevel Intervention Strategies Targeting Immunization in Community Settings) parent-level intervention includes a low literacy pre-visit HPV vaccine notification post card in the parent's preferred language.
BEHAVIORALHPV MISTICS- HPV Vaccine Champion Level
The HPV MISTICS (Multilevel Intervention Strategies Targeting Immunization in Community Settings) system-level intervention involves training an HPV Vaccine Champion at each FQHC on the provider and parent EBIs to monitor and share clinic HPV initiation and completion rates with providers, and to implement reminder/recall systems for subsequent vaccine doses
Sponsors
Florida Department of Health
Health Choice Network
H. Lee Moffitt Cancer Center and Research Institute
Study design
Allocation
RANDOMIZED
Intervention model
SEQUENTIAL
Primary purpose
PREVENTION
Masking
NONE
Intervention model description
Hybrid Type 1 implementation design which will allow the team to examine both effectiveness of HPV MISTICS and implementation outcomes in a single study. Implementation outcomes will be evaluated using the RE-AIM Qualitative Evaluation for Systematic Translation (RE-AIM QuEST) framework, a mixed-methods framework to identify implementation barriers and facilitators while assessing implementation outcomes (e.g., reach, adoption, implementation, maintenance/sustainability) with a focus on evaluating equity across these outcomes.
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
Yes
Inclusion criteria
* For Staff: * 18 years of age or older * Working within the participating Federally Qualified Health Center system * Able to read, write and speak English * For Providers: * 18 years of age or older * Working within the participating Federally Qualified Health Center system * Interacting with parents of adolescents ages 11-17 * Able to read, write and speak English * For parents: * Parent of 11-17 year old child that has received care within the prior two months at one of the participating Federally Qualified Health Centers * Whose child has not initiated or completed the HPV vaccine series at the time of their last visit * Able to read, write and speak English or Spanish, or Haitian Creole
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Effectiveness: HPV Vaccine series initiation rates | at 5 years | HPV vaccine series initiation (1st dose) rates among adolescents ages 11-17 will be determined on a monthly basis as well as annually. Providers' vaccination rate data for their patient panel (using Florida SHOTS - a free, statewide centralized online immunization information system) will be compared to the National Immunization Survey-Teen (NIS-TEEN) data for the state of Florida. |
| Effectiveness: HPV Vaccine series completion rates | at 5 years | HPV vaccine series completion (2nd and 3rd dose) rates among adolescents ages 11-17 will be determined on a monthly basis as well as annually. Providers' vaccination rate data for their patient panel (using Florida SHOTS - a free, statewide centralized online immunization information system) will be compared to the National Immunization Survey-Teen (NIS-TEEN) data for the state of Florida. |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Proportion of Healthcare providers who participate in the intervention | at 5 years | The proportion of health care providers who participate in the intervention, measured by contact log data. |
| Proportion of Healthcare Providers, Rural vs Urban | at 5 years | The proportion of health care providers in rural vs urban Federally Qualified Health Centers in network that participate. |
| Implementation outcome: Reach | at 5 years | The intervention's implementation will be evaluated for reach - proportion of eligible patients that receive the intervention. |
| Intervention Sustainability: Health care Providers | at 5 years | Long term intervention effects and use over time will be determined semi-structured interviews of providers |
| Intervention Sustainability: Healthcare staff | at 5 years | Long term intervention effects and use over time will be determined semi-structured interviews of health care staff. |
| Proportion of Health Care providers who complete training | at 5 years | The proportion of participating health care providers and staff who complete training per site will be measured using the training attendance log |
| Implementation outcome: Reach demographics | at 5 years | The intervention's implementation will be evaluated for reach - demographics of patients reached. |
Countries
United States
Outcome results
None listed