The Relationship Between Driving Pressure, Mechanical Power, Oxygenation and Saturation Indices: Retrospective Observational Study

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT05677165

Enrollment

361

Registered

2023-01-10

Start date

2020-03-18

Completion date

2021-11-28

Last updated

2023-01-10

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Acute Respiratory Distress Syndrome, Pneumonia

Keywords

acute respiratory distress syndrome, pneumonia, oxygenation index, saturation index

Brief summary

By using Mechanical Power and Driving Pressure instead of Pmean we calculate new oxygen saturation indices like Driving Pressure Oxygen Index (OIDP), Dynamic Power Oxygen Index (OIMPdyn), Total Power Oxygen Index (OIMPtot), Driving Pressure Saturation Index (OSIDP), Dynamic Power Saturation Index (OSIMPdyn) ve Power Saturation Index (OSIMPtot). New oxygenation and saturation indices are able to predict ICU mortality better than the conventional indexes and rates.

Interventions

None listed

Study design

Observational model

OTHER

Time perspective

RETROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Healthy volunteers

Inclusion criteria

\- Patients with a diagnosis of Covid-19 related Acute Respiratory Syndrome (C-ARDS) which hospitalized in Bakirköy Dr. Sadi Konuk Training and Research Hospital intensive care unit

Exclusion criteria

* Patients who did not receive invasive mechanical ventilation support. * Patients who stayed in the intensive care unit for less than 24 hours. * Patients with missing data * Patients who received mechanical ventilation support for less than 24 hours * Patients with Chronic Obstructive Pulmonary Disease (COPD). * Patients with congestive heart failure * Patients who underwent tube thoracostomy due to tension pneumothorax * Patients who received Extracorporeal Membrane Oxygenation (ECMO) support

Design outcomes

Primary

Measure	Time frame	Description
In hospital mortality	28 days	we estimate hospital mortality mortality by calculating new oxygenation index

Secondary

Measure	Time frame	Description
Mechanical ventilatory free days	30 days	we estimate hospital mortality mortality by calculating new saturation index

Countries

Turkey (Türkiye)

Outcome results