Celiac Disease in Children
Conditions
Brief summary
The investigators conducted a retrospective, observational cohort study which enrolled CD subjects aged 2-18y, diagnosed between Jan 2016 and Dec 2020. Demographic and laboratory data were collected at diagnosis and 1y after adherence to GFD. ID was determined according to hemoglobin and ferritin levels. The investigators compared CD subjects with and without ID at CD diagnosis in relation to TTG normalization at 1y.
Interventions
OTHERGluten free diet
All subjects initiated a gluten free diet as mandated by their diagnosis of Celiac disease, regardless of the study
Sponsors
Meir Medical Center
Study design
Observational model
COHORT
Time perspective
RETROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
2 Years to 18 Years
Healthy volunteers
No
Inclusion criteria
* Children (male and female) diagnosed with CD * Age 2-18y
Exclusion criteria
* Total IgA deficiency * Anemia due to other causes - anyone with anemia and normal or elevated ferritin levels (e.g. thalassemia, spherocytosis) * Other chronic conditions increasing the risk of anemia or falsely elevated ferritin (e.g. inflammatory bowel disease, chronic kidney disease, infection)
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| TTG normalization | 1 year from gluten free diet initiation | normalization of tissue transglutaminase antibody |
Countries
Israel
Outcome results
None listed