Aging, Cognitive Decline, Cognitive Impairment, Mild, Dementia
Conditions
Brief summary
This study investigated the efficacy of the Silvia program, a mobile-based multidomain intervention, to improve cognitive function and health-related outcomes of older adults with a high risk of dementia. We compare its effects to a conventional paper-based multidomain program on various health indicators related to risk factors of dementia.
Interventions
DEVICEmobile-based
Participants who were randomly assigned to the mobile-based intervention group were provided multidomain programs based on scientific evidence of ways to improve brain-health and reduce dementia risk for 10 minutes per day and at least 50 minutes per week.
OTHERpaper-based
Participants who were randomly assigned to the paper-based intervention group were provided with the Korean version of the dementia prevention booklet published by the WHO.
Sponsors
Chosun University Hospital
Silvia Health
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
PREVENTION
Masking
SINGLE (Outcomes Assessor)
Eligibility
Sex/Gender
ALL
Age
60 Years to 75 Years
Healthy volunteers
No
Inclusion criteria
1. experiencing subjective cognitive decline, 2. had a smart phone and could use it, and 3. understood the purpose and process of this study.
Exclusion criteria
1. major psychiatric disorders 2. dementia, 3. degenerative brain diseases 4. severe or unstable heart diseases 5. neurological or psychological diseases that affected cognitive functioning 6. severe vision or hearing impairment, 7. current participation in a cognitive training program 8. does not know how to use mobile devices.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Change from baseline Korean version of the Repeatable Battery for the Assessment of Neuropsychological status at 12 weeks | baseline and after the 12-week intervention | Cognitive function |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Change form baseline Korean version of the prospective and retrospective memory questionnaire(K-PRMQ) at 12 weeks | baseline and after the 12-week intervention | Self-reported memory failures |
| Change from baseline Center for Epidemiological Studies Depression (CES-D) questionnaire at 12 weeks | baseline and after the 12-week intervention | Depression |
| Change from baseline Korean version of the mini-mental state examination, 2nd edition(K-MMSE-2) at 12 weeks | baseline and after the 12-week intervention | Cognitive function |
| Change from baseline Perceived Stress Scale (PSS) at 12 weeks | baseline and after the 12-week intervention | Stress |
| Change from baseline EuroQoL 5-Dimension 5-Level(EQ-5D-5L) at 12 weeks | baseline and after the 12-week intervention | Health-related Quality of life |
| Change from baseline State-Trait Anxiety Inventory-X-1(STAI-X-1) at 12 weeks | baseline and after the 12-week intervention | Anxiety |
Countries
South Korea
Outcome results
None listed