Skip to content

Glaucoma Assessment Via Reading Ability

Glaucoma Assessment Via Reading Ability Using Logarithmic Chinese Reading Acuity Chart

Status
UNKNOWN
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT05673954
Enrollment
200
Registered
2023-01-06
Start date
2023-01-01
Completion date
2024-02-29
Last updated
2023-01-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Glaucoma, Primary Open Angle

Brief summary

To explore a quantitative glaucoma evaluation tool of glaucoma through the dynamic evaluation of reading ability based on logarithmic Chinese reading acuity chart (C-READ), and investigate its feasibility.

Detailed description

Glaucoma is the most common cause of irreversible blindness in the world, and it's marked by the gradual loss of retinal ganglion cells and their optic nerve fibres. Early detection and treatment can successfully prevent the disease's development and prevent blindness. Glaucoma sufferers' near visual qualities, particularly their ability to read, might be compromised. Patients can, however, regain some comfortable reading capacity following glaucoma therapy. The logarithmic Chinese reading acuity chart (C-READ) can be beneficial as a tool for functional vision evaluation, and there is rising clinical interest in this well-standardized, calibrated reading chart. Reading chart standards that allow for equal assessment of reading factors such as acuity and speed are currently lacking. The C-READ approach as a judge of glaucoma patients' status lacks theoretical support, and functional visual evaluation tools are still in their infancy. Therefore, we want to complete these tasks: 1) develop a dynamic analytic system and improve the evaluation criteria for the C-READ testing procedure; 2) confirm the usefulness of C-READ for early glaucoma screening through clinical studies. C-READ will provide a reliable and cost-effective screening technique that is convenient, affordable, and noninvasive.

Interventions

DIAGNOSTIC_TESTC-Read test

C-Read is a reliable and valid clinical tool for quantitatively testing the reading ability of readers of simplified Chinese characters.

Sponsors

Peking University
Lead SponsorOTHER

Study design

Observational model
CASE_CONTROL
Time perspective
PROSPECTIVE

Eligibility

Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
Yes

Inclusion criteria

* Primary open angle glaucoma in at least 1 eye or labelled as a glaucoma suspect by a glaucoma specialist * Age ≥18 years old * with open angles on gonioscopy * best-corrected visual acuity ≥0.5 * spherical refraction within ±5.0 diopters (D), and/or cylinder correction within 3.0 D

Exclusion criteria

* eyes with any evidence of physical abnormality of the iris or pupils on slit-lamp examination * eyes with a history of trauma or inflammation * undergone an intraocular surgery or laser within the previous 6 months/except uncomplicated cataract surgery * using systemic or topical medications that could affect pupil responses, including pilocarpine or atropine * presence of any media opacities that prevented good quality OCT or fundus images * presence of any retinal or neurological disease other than glaucoma * abnormal ocular motility that prevents binocular fixation (eg, nystagmus, strabismus) * with severe systemic diseases or psychiatric disorders

Design outcomes

Primary

MeasureTime frameDescription
The Relationship between Reading Ability and C-READ Test ResultsJanuary 2023 to December 2023The Relationship between Reading Ability and C-READ Test Results

Contacts

Primary ContactChun Zhang
zhangc1@yahoo.com18301031059

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026