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MRI-Based Structural Changes in Lumber Spine in Subjects With Discogenic Low Back Pain After Mckenzie Exercises.

MRI-Based Structural Changes in Lumber Spine in Subjects With Discogenic Low Back Pain After Mckenzie Exercises.

Status
UNKNOWN
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT05673616
Enrollment
40
Registered
2023-01-06
Start date
2023-02-01
Completion date
2023-09-30
Last updated
2023-01-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Mechanical Low Back Pain

Keywords

Physical therapy; Intervertebral disc; Magnetic resonance imaging; Low Back Pain

Brief summary

In the rehabilitation department, we are working with patients of low back pain for routine management and as well as for research. Still now, the biomechanical ground proofing the beneficial effects of McKenzie Mechanical diagnosis and therapy on non-mechanical low back pain has not been studied in depth. This qausi-experimental study will provide expert-level evidence using gold standard MRI findings to add McKenzie MDT in routine treatment of the condition.

Detailed description

OBJECTIVES: The objectives of this study will be: 1. To determine the effects of McKenzie Mechanical Diagnosis and Therapy (MDT) on MRI-based structural changes in Pateints with mechanical low back pain. 2. To determine the effects of McKenzie MDT on Pain and Disabaility scores in patients with mechanical low back pain. 3. To determine the effects of McKenzie MDT on Disabaility scores in patients with mechanical low back pain. HYPOTHESIS: Alternate Hypothesis: The Mckenzie MDT will be effective in improving the MRI-based structural changes, pain and disability caused by the mechanical low back pain. Null Hypothesis: The Mckenzie MDT will not be effective in improving the MRI-based structural changes, pain and disability caused by the mechanical low back pain. Research Design: Quasi - experimental Study. Clinical setting: Foundation University College of Physical Therapy, Foundation University Islamabad. Study duration: 12 months Sampling technique: Non-probability Purposive sampling Intervention to be given After assessing the patient for eligibility, following intervention regime will be followed: 1. st consultation-Day 1: In standing right side gliding will be repeated for ten to twenty times. Afterwards, extension will be repeated in lying position for ten to twenty times. The protocol will be repeated after every three hours. 2. nd consultation- Day 3: Extension will be repeated in lying position for ten to twenty times. The protocol will be repeated after every three hours. 3. rd consultation- Day 15: After two weeks of initial consultation, the patient will be taught to perform slouch-overcorrect on day 1 followed by flexion on day 2 in lying position and accompanied by flexion for 5 days in sitting position and finally flexion in standing will be performed. The exercises will be repeated for 10 times and followed by extension in standing exercises. Significance: McKenzie mechanical diagnosis and therapy (MDT) is more effective than other therapeutic physiotherapies. But, the biomechanical ground proofing of the beneficial effects of MDT on non-mechanical low back pain has not been studied in depth. This gap will be filled by the gold standard MRI imaging technology that allows non-invasive and more detailed view of intervertebral disc. This study will emphasize the healthcare practitioners regarding the cellular level benefits of said intervention and hence decrease the surgical cost by early treatment through physical therapy and rehabilitation. This study will emphasize the healthcare practitioners regarding the cellular level benefits of said intervention and hence decrease the surgical cost by early treatment through physical therapy and rehabilitation.

Interventions

After two weeks of initial consultation, the patient will be taught to perform slouch-overcorrect on day 1 followed by flexion on day 2 in lying position and accompanied by flexion for 5 days in sitting position and finally flexion in standing will be performed. The exercises will be repeated for 10 times and followed by extension in standing exercises.

Sponsors

Foundation University Islamabad
Lead SponsorOTHER

Study design

Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
HEALTH_SERVICES_RESEARCH
Masking
NONE

Intervention model description

Inclusion Criteria 1. Patients having Discogenic LBP referred from hospital. 2. Male and female both 3. Ptients hving Modic changes in MRI. 3.Otherwise, healthy patients with age range from 18 to 55 years. Exclusion criteria: 1. Patients with non-mechanical LBP 2. Patients not meeting age range 3. Patients with any major co-morbidity 4. Any type of systemic illness

Eligibility

Sex/Gender
ALL
Age
18 Years to 55 Years
Healthy volunteers
No

Inclusion criteria

Both genders having low back pain. Patients having modic changes in MRI. Otherwise healthy patients with age range from 18 - 55 years.

Exclusion criteria

Patients with non-mechanical LBP Patients not meeting age range Patients with any major co-morbidity

Design outcomes

Primary

MeasureTime frameDescription
MRI changesAt baseline and 4 weeksfatty infiltration and modic changes

Secondary

MeasureTime frameDescription
Pain intensity assessed by numeric pain rating scaleAt baseline and 4 weeksPain will be assessed by numeric pain rating scale
Disability will be assessed by Roland-Morris Low Back Pain and Disability Questionnaire (RMQ)At baseline and 4 weeks

Countries

Pakistan

Contacts

Primary ContactMadiha Ashfaq, DPT, MS-CPPT
madiha.ashfaq@fui.edu.pk+923325143479
Backup ContactSidra Qureshi, DPT,MS-WHPT
Sidra.qureshi@fui.edu.pk03338223868

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026