Pain
Conditions
Brief summary
Analgesia Nociception Index (ANI) has been proposed for the evaluation of the nociception-antinociception balance in the perioperative period. In pediatric patients with Moyamoay disease, where the management of analgesia may be rendered difficult by pharmacological changes, we hypothesised that the monitoring of analgesia with ANI would reduce intraoperative opioid consumption during EDAS surgery.
Interventions
DEVICEANI (Analgesia/Nociception Index) monitoring
Intraoperative analgesia was provided by injection of sufentanil, which was performed according to ANI monitor.
DEVICEstandard monitoring
Intraoperative analgesia was provided by injection of sufentanil, which was performed according to the clinician's assessment.
DRUGSufentanil
Sufentanil
Sponsors
Seoul National University Hospital
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
OTHER
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
No minimum to 18 Years
Healthy volunteers
No
Inclusion criteria
* Pediatric patients receiving EDAS surgery for Moyamoya disease
Exclusion criteria
* ASA (American society of anesthsiologists classification) 4-5 * Emergency surgery * patients with chronic pain on medication
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| the mean hourly intraoperative sufentanil requirement | from induction of anesthesia to end of operation, about 5 hours |
Secondary
| Measure | Time frame |
|---|---|
| the amount of non-opioids analgesic requirements | from induction of anesthesia to end of operation, about 5 hours |
| the amount of vasoactive agents requirements | from induction of anesthesia to end of operation, about 5 hours |
Countries
South Korea
Contacts
Primary ContactEun-hee Kim
Outcome results
None listed