Aortic Valve Stenosis, Sarcopenia
Conditions
Keywords
sarcopenia, survival, TAVI
Brief summary
The goal of this observational study is to compare the overal survival after transcatheter aortic valve implantation (TAVI) according to sarcopenia status evaluated from preprocedural CT scans. The main question it aims to answer is: • Is CT evaluated sarcopenia an independent predictor of overal survival after TAVI?
Detailed description
The patients suffering from aortic valve stenosis, that are not eligible for cardiosurgery were indicated to miniinvasive transcatheter aortic valve implantation (TAVI). The follow up of 930 patients were done in time interval from 1 to 11 years. In every patient the preprocedural CT scans were done. From these CT scans the L3 cross sections will be used for sarcopenia evaluation. Then we will statisticaly evaluate the overal survival after TAVI procedure in the relation with sarcopenia status. We will answer the main question: Is CT evaluated sarcopenia an independent predictor of overal survival after TAVI?
Interventions
DIAGNOSTIC_TESTCT evaluated sarcopenia
At L3 level of CT scan we will measure the area and density of muscles and fat tissue. We devided the patients to sarcopenia and non-sarcopenia groups according to these values.
Sponsors
Nemocnice AGEL Trinec-Podlesi a.s.
Study design
Observational model
COHORT
Time perspective
RETROSPECTIVE
Eligibility
Sex/Gender
ALL
Healthy volunteers
No
Inclusion criteria
* patients udergone TAVI procedure
Exclusion criteria
* patients with incomplete TAVI procedure, patients without clinical follow up
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Overal survival | 11 years | Time from the TAVI procedure to death |
Countries
Czechia
Outcome results
None listed