Peanut and Tree Nut Allergy
Conditions
Keywords
Peanut allergy, tree nut allergy, peanut immunotherapy, anaphylaxis, real life
Brief summary
Food allergy is an immune reaction, triggered by food protein allergens, of varying severity, from mild local reaction to life threatening anaphylaxis and fatalities. Peanut is a plant from the botanical family of the Fabaceae, more commonly known as legumes. The prevalence of peanut and tree nut allergy is increasing. In France (ELFE cohort), it is estimated to 0.93%. The tree nuts include mainly almond, hazelnut, pistachio, cashew nut, walnut, pecan nut and Brazil nut. Allergy's prevalence is estimated to 0.54% in children up to 5.5 years. Peanut allergy is a main cause of anaphylaxis and deaths due to food allergy. Recurrence of food allergy is a main concern. The risk has been estimated to 10% per year for peanut. In France, Data in real-life on the rate of recurrence of allergic reactions and anaphylaxis to peanut/tree-nut as well as risk factors, are lacking. The objective of this study is to assess the frequency of allergic reaction to peanut and tree-nuts, to describe the reactions' characteristics and risk factors.
Interventions
None listed
Sponsors
University Hospital, Lille
Study design
Observational model
COHORT
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
No minimum to 18 Years
Healthy volunteers
No
Inclusion criteria
* Confirmed allergy to peanuts and/or nuts
Exclusion criteria
* Other chronic diseases, except allergic comorbidities (asthma, rhinitis, atopic dermatitis, other food allergy)
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| the number of episode of allergic reactions in real life | At 1 year |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| the severity of the allergic reactions according to a validated scale (FASS scale) | At 1 year | — |
| interview for the characteristics of the allergic reactions | At 1 year | the characteristics of the reactions: symptoms, triggering food and quantity, location, emergency kit available, treatment administered, evolution (hospitalization or emergency room) |
| interview to defined the risks factor associated | At 1 year | risk factors for reaction: * Other known allergies * Asthma * Atopic dermatitis * Allergic rhinoconjunctivitis * Patient characteristics: sex, age |
Countries
France
Outcome results
None listed