Does a Clinical Support System for Parenteral Nutrition (PN) Facilitate the Judgement on Choosing the Most Effective Commercial Solution Per Patient (and Modify it, if Necessary)?

Does a Clinical Support System for Parenteral Nutrition (PN) Facilitate the Judgement on Choosing the Most Effective Commercial Solution Per Patient (and Modify it, if Necessary)? Is This Solution an Appropriate Alternative to Customized PN for Optimum Nutrition Outcome?

Status

Completed

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT05670613

Acronym

CDSS

Enrollment

Registered

2023-01-04

Start date

2021-02-12

Completion date

2022-09-18

Last updated

2023-01-04

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Clinical Decision Support System

Brief summary

Standard formulas of PN have been developed and provided to patients. Only few randomized controlled studies compared standardized vs individualized PN. Individually tailored PN, only if standard PN solutions do not meet patient's nutritional needs. ASPEN society recommends the use computerized prescribing. Technology has enabled the incorporation of medical guidelines in CDSSs. New approach: Comparison of patient's calculated nutritional needs with commercial available solutions.

Interventions

OTHERCDSS Canceling

The use of Clinical Decision Support System in Parenteral Nutrition

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

SCREENING

Masking

NONE

Eligibility

Sex/Gender

ALL

Age

18 Years to 85 Years

Healthy volunteers

Inclusion criteria

* Hospitalize Patients unable to be fed via gastrointestinal tract. * Hemodynamically stable patients. * PN regimen should remain the same for the first 3 days.

Exclusion criteria

* Hemodynamically unstable. * Anticipated need for parenteral nutrition less than 5 days.

Design outcomes

Primary

Measure	Time frame	Description
Estimate of Macro and Micro Nutrient Needs for PN.	0 months - 12 months	Estimation of macro and micro nutrient needs for PN by CDSS: amino acids, carbohydrates, lipid, electrolytes, energy and fluids.
Estimate the difference between actual PN energy needs (kcal per day) and energy provided in the PN solutions available in the market (kcal per 100ml).	0 months - 12 months	Compare Ready to Use PN solutions with patient's actual nutritional energy needs in order to customize PN for optimum nutrition outcome.
Estimate the difference between actual PN needs and nutrient content of Ready to use Solution for PN available in the market.	0 months - 12 months	Compare Ready to Use PN solutions on total grams of amino acids with patient's actual nutritional needs on total grams of amino acids in order to optimize patient's PN for better nutritional outcome.
Difference of time spent on estimation of PN needs when conducted by hand and CDSS.	0 months - 12 months	Compare time spent for a) calculation of nutritional needs, b) prescription and c) transcription by using CDSS or made by hand.

Countries

Greece

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026