Aberration, Corneal Wavefront, Glaucoma, Suspect
Conditions
Keywords
Glaucoma suspect, Post-lasik
Brief summary
selective alpha-2 receptor agonists cause changes in intraocular pressure and pupillary size thus may affect patient quality of life.
Detailed description
In this research, we will analyze the effect of selective alpha-2 receptor agonists on the human eye and investigate ocular changes over 6 months after its topical use.
Interventions
DRUGLow dosage selective alpha-2 receptor agonists topical eyedrop
Using selective alpha-2 receptor agonists eyedrop in both groups with 0.2% concentration.
DRUGHigh dosage selective alpha-2 receptor agonists topical eyedrop
Using selective alpha-2 receptor agonists eyedrop in both groups with 0.02% concentration.
Sponsors
Benha University
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
SUPPORTIVE_CARE
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
18 Years to 50 Years
Healthy volunteers
No
Inclusion criteria
* Glaucoma suspect cases. * post-refractive surgery cases.
Exclusion criteria
* Cases with prostatic hyperplasia or diabetics that may alter the measurements of pupillary diameter. * Cases with previous history of any retinal intervention or other drugs that may alter intraocular pressure measurements.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Intraocular pressure | Baseline and 6 months after regular use of the topical eyedrops | Changes in intraocular pressure measured in mmHg by applanation tonometry |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Pupillary diameter | Baseline and 6 months after regular use of the topical eyedrops | Changes in the pupillary diameter measured in mm by handheld pupillometer |
Countries
Egypt
Contacts
Primary ContactAhmed Abdelshafy, MD
Backup ContactMarwa Abdelshafy, MD
Outcome results
None listed