Respiratory Muscles, Thoracic Surgery, Video Assisted Thoracoscopic Surgery
Conditions
Keywords
Lung cancer, functional capacity
Brief summary
The most commonly treatment for early stage non-small cell lung cancer (NSCLC) is lobectomy. Different surgical interventions during lobectomy are thought to have different effects on respiratory functions and exercise capacities. The aim of this study was to evaluate respiratory muscle strength, functional exercise capacity, and diaphragmatic thickness in groups that underwent lobectomy with standard thoracotomy, muscle sparing thoracotomy, and video-assisted thoracic surgery (VATS).
Detailed description
The most commonly treatment for early stage non-small cell lung cancer (NSCLC) is lobectomy. Different surgical interventions during lobectomy are thought to have different effects on respiratory functions and exercise capacities. The aim of this study was to evaluate respiratory muscle strength, functional exercise capacity, and diaphragmatic thickness in groups that underwent lobectomy with standard thoracotomy, muscle sparing thoracotomy, and video-assisted thoracic surgery (VATS). In this study we will evaluate respiratory muscle strength, functional exercise capacity, diaphragmatic thickness, postoperative pulmonary complications, pain, dyspnea, pulmonary function, functional status, anxiety and depression.
Interventions
None listed
Sponsors
Hacettepe University
Study design
Observational model
COHORT
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to 75 Years
Healthy volunteers
No
Inclusion criteria
* Being a lung cancer patient scheduled for standard thoracotomy, muscle sparing thoracotomy, or lobectomy with VATS, * Being clinically stable, * Volunteering to participate in the study, * be between the ages of 18-75, * To be cooperative in the tests to be done.
Exclusion criteria
* Having an orthopedic and neurological condition that prevents walking, - Having undergone any surgery on the thoracic wall, * Diagnosed with small cell lung cancer.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Respiratory muscle strength (inspiration) change | The day before the operation. | Respiratory muscle strength will measure by measuring mouth pressure and using maximal inspiratory pressure (MIP) values. Preoperative and postoperative value differences will be calculated. |
| Respiratory muscle strength (expiration) change | The day before the operation. | Respiratory muscle strength will measure by measuring mouth pressure and using maximal expiratory pressure (MEP) values. Preoperative and postoperative value differences will be calculated. |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Postoperative Pulmonary Complication | Postoperative first-fifth days. | Postoperative pulmonary complications will be evaulate by Melbourne Group Scale. If more than 4 parameters are positive, it will be considered as having postoperative pulmonary complication. |
| Functional exercise capacity | The day before the operation. | 6-minute walk test (6MWT) will be used to evaluate functional exercise capacity. |
| Postoperative pain | The operative day after the operation. | Visual anolog scala will be used to measure pain. Zero is considered as no pain an ten s considered as no maximal pain. |
| Dyspnea | The day before the operation. | Dyspnea will be evaulate by Modifiye Medical Research Council Dyspnea Scale (mMRC). |
| Pulmonary function (FVC) | The day before the operation. | Pulmonary function will be evaulate by pulmonary function test. FVC will be measured in liter. |
| Pulmonary function (FEF25-75) | The day before the operation. | Pulmonary function will be evaulate by pulmonary function test. FEF25-75 will be measured in liter. |
| Pulmonary function (PEF) | The day before the operation. | Pulmonary function will be evaulate by pulmonary function test. PEF will be measured in liter. |
| Functional Status | The day before the operation. | Karnofsky Performance Status Scale will be used to evaluate functional status. It will be used i to assess the preoperative condition. |
| Anxiety and Depression | Postoperative first-fifth days. | Anxiety and depression will be evaulate by Hospital Anxiety and Depression Scale. 7 of the survey questions question depression and 7 of them question anxiety. |
| Pulmonary function (FEV1) | The day before the operation. | Pulmonary function will be evaulate by pulmonary function test. FEV1 will be measured in liter. |
| Diaphragmatic thickness | The day before the operation. | Ultrasound will be used to measure diaphragmatic thickness. |
Countries
Turkey (Türkiye)
Outcome results
None listed