Invasive Mechanical Ventilation
Conditions
Keywords
Mechanical ventilation, ventilator-induced lung injury, ARDS, artificial intelligence
Brief summary
Invasive mechanical ventilation is one of the most important and life-saving therapies in the intensive care unit (ICU). In most severe cases, extracorporeal lung support is initiated when mechanical ventilation is insufficient. However, mechanical ventilation is recognised as potentially harmful, because inappropriate mechanical ventilation settings in ICU patients are associated with organ damage, contributing to disease burden. Studies revealed that mechanical ventilation is often not provided adequately despite clear evidence and guidelines. Variables at the ventilator and extracorporeal lung support device can be set automatically using optimization functions and clinical recommendations, but the handling of experts may still deviate from those settings depending upon the clinical characteristics of individual patients. Artificial intelligence can be used to learn from those deviations as well as the patient's condition in an attempt to improve the combination of settings and accomplish lung support with reduced risk of damage.
Interventions
OTHERArtificial Intelligence-based Decision support
Decision support to optimise invasive mechanical ventilation settings
Sponsors
Technische Universität Dresden
Study design
Observational model
OTHER
Time perspective
RETROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Inclusion criteria
• Subjects who are 18 years or older and receive invasive mechanical ventilation for \> 4 hours
Exclusion criteria
• Patients receiving one-lung ventilation
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Relative time of same device settings of the health care provider and the IntelliLung algorithm | From date of intubation to date of extubation or date of discharge, which ever came first, assessed up to 12 month |
Countries
Germany, Serbia, Spain, Switzerland, United States
Contacts
CONTACTJakob Wittenstein, MD
CONTACTThea Koch, PhD
PRINCIPAL_INVESTIGATORJakob Wittenstein, MD
University Hospital Carl Gustav Carus at Technischen Universität Dresden, Germany
Outcome results
None listed