Bone Metastases
Conditions
Brief summary
This study will carry out a prospective cohort study to study the effect of different primary leison treatment modes on disease control, quality of life, economic cost and survival period of patients with bone metastases from breast cancer and lung cancer by giving radiotherapy or palliative surgery or not giving local treatment for the primary lesion in patients with bone metastases from breast cancer or lung cancer
Interventions
RADIATIONradiotherapy
radiotherapy
PROCEDUREpalliative surgery
palliative surgery
Sponsors
Shanghai 6th People's Hospital
Study design
Allocation
NON_RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
1. HR positive breast cancer patients with bone metastasis or Non-small-cell lung cancer patients with bone metastasis； 2. Aged over 18; 3. ECOG：0-1； 4. Patients who benefit clinically(CR+PR) after 6 months of treatment.
Exclusion criteria
1. The expected life span is less than 3 months; 2. Have serious cardiovascular and cerebrovascular diseases, blood coagulation dysfunction, and cannot tolerate surgery; 3. Allergies to narcotic drugs; 4. The patient refused the treatment decision of the integrated team.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Disease control rate at 1 year | 1 year | Disease control rate |
Secondary
| Measure | Time frame |
|---|---|
| Progression-Free Survival | 1 year |
| Overall Survival | 1 year |
Outcome results
None listed