Local Treatment for Bone Metastases

Study on Local Treatment for Patients With Bone Metastases

Status

Not yet recruiting

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT05665439

Enrollment

348

Registered

2022-12-27

Start date

2023-03-31

Completion date

2026-03-31

Last updated

2023-03-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Bone Metastases

Brief summary

This study will carry out a prospective randomized controlled study to study the effect of different local treatment on disease control, quality of life, economic cost and even survival period of patients by randomly giving local radiotherapy or observation to patients with newly diagnosed bone metastases or patients with bone metastases after vertebroplasty.

Interventions

RADIATIONradiation

radiation for patients with newly diagnosed bone metastases or patients with bone metastases after vertebroplasty

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

TREATMENT

Masking

NONE

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Healthy volunteers

Inclusion criteria

1. Patients who are definitely diagnosed as malignant tumor by pathology or cytology; 2. At least one bone metastasis site; 3. Aged over 18; 4. ECOG：0-1； 5. The pain score is less than 5 or after vertebroplasty within 1 month.

Exclusion criteria

1. The expected life span is less than 3 months; 2. Spinal metastatic tumor stability score (SINS) is greater than 7; 3. Spinal cord compression; 4. The patient refused the treatment decision of the integrated team.

Design outcomes

Primary

Measure	Time frame	Description
Disease control rate at 1 year	1 year	Disease control rate

Secondary

Measure	Time frame
Progression-Free Survival	1 year
Overall Survival	1 year

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026