Skip to content

Validity and Reliability of Lower Extremity Position Test in Patients with Multiple Sclerosis

Validity and Reliability of Lower Extremity Position Test in Patients with Multiple Sclerosis

Status
Completed
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT05663541
Enrollment
90
Registered
2022-12-23
Start date
2022-10-24
Completion date
2023-07-24
Last updated
2024-12-05

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Multiple Sclerosis, Proprioceptive Disorders, Reliability, Sensory Impairments, Validity

Brief summary

Sensory disorders are one of the most important problems in individuals with MS, and these disorders are among the first symptoms of MS. Loss of sense of proprioception is particularly common in patients with MS. Studies show that assessment methods for the quantitative measurement of sensory disorders are lacking. Especially in the clinic, there is no evaluation method that evaluates the sense of proprioception. Therefore, the aim of this study perform the validity and reliability study of the lower extremity position test to evaluate proprioception sense in individuals with MS.

Interventions

DIAGNOSTIC_TESTLower extremity position test

Assessing proprioception of the lower extremity of individuals multiple sclerosis

Sponsors

Pamukkale University
Lead SponsorOTHER

Study design

Observational model
CASE_ONLY
Time perspective
CROSS_SECTIONAL

Eligibility

Sex/Gender
ALL
Age
20 Years to 65 Years
Healthy volunteers
No

Inclusion criteria

* 20-65 years old * EDSS score between 0-5 * Person who has not had an attack in the last 1 month or who is not in the attack period * Person without systemic disease such as hypertension, heart disease, Diabetes Mellitus, hyperlipidemia, malignancy * Person who has not undergone surgery that restricts balance function in the lower extremity. * Person without hip, knee and ankle contracture * Person who does not have additional neurological disease * Person who does not use vestibulosupressants or drugs that may cause neuropathy and does not have a history of alcohol use * To have full cooperation and adaptation to the work * Individuals who agree to receive treatment will be included in the study.

Exclusion criteria

* Being younger than 20 years old and over 65 years old * Being in the attack period * Hip, knee or ankle contracture * Being greater than EDSS 5 * Having systemic diseases such as hypertension, heart disease, Diabetes Mellitus, hyperlipidemia, malignancy * Having an additional neurological disease * Having a vestibulospressant or drug or alcohol use habit that causes neuropathy * Not cooperating and adapting to the work

Design outcomes

Primary

MeasureTime frameDescription
Sensorial Assessment-2through study completion, an average of 1 yearKinesthesia (Inclinometer)
Balance Assessment-2through study completion, an average of 1 yearDynamic Balance via time up and go
Walking Speed Assessmentthrough study completion, an average of 1 yearThe 10 meter walk test
Sensorial Assessment-1through study completion, an average of 1 yearLower Extremity Position test
Balance Assessment-1through study completion, an average of 1 yearStatic Balance via single leg stance

Secondary

MeasureTime frameDescription
Expanded Disability Status Scale (EDSS)through study completion, an average of 1 yearRanges from 0 to 10 in 0.5 unit increments that represent higher levels of disability.
Demographic Assessmentthrough study completion, an average of 1 yearDemographic form

Countries

Turkey (Türkiye)

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026