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Effect of Intraoperative Allogeneic Blood Transfusion on Postoperative Pulmonary Complications

Effect of Intraoperative Allogeneic Blood Transfusion on Postoperative Pulmonary Complications in Elective Spinal Surgery: a Retrospective Cohort Study

Status
Completed
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT05661838
Enrollment
272
Registered
2022-12-22
Start date
2013-08-01
Completion date
2020-10-31
Last updated
2022-12-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Pulmonary Complication, Spinal Fusion, Transfusion

Brief summary

Elective spine surgery is associated with a high incidence of perioperative complications, including peri- and postoperative pulmonary complications (PPCs), which occur in nearly 4% of patients. More than 40% of all deaths after elective spine surgery are attributed to PPCs. However, whether it influences risk of other PPCs is unclear.

Interventions

PROCEDUREtransfusion

transfusion

Sponsors

Second Affiliated Hospital, School of Medicine, Zhejiang University
Lead SponsorOTHER

Study design

Observational model
CASE_CONTROL
Time perspective
RETROSPECTIVE

Eligibility

Sex/Gender
ALL
Age
9 Years to 82 Years
Healthy volunteers
No

Inclusion criteria

* Patients were included if they underwent elective spine surgery (e.g. multi-segmental thoracic, lumbar, or thoracolumbar spine surgery) at the Second Hospital of Zhejiang University School of Medicine from August 1, 2013 to October 31, 2020

Exclusion criteria

* combined anterior-posterior surgery * growth rod adjustment surgery * spinal tumor. * surgery took fewer than 3 hours.

Design outcomes

Primary

MeasureTime frameDescription
Correlation between blood transfusion and postoperative pulmonary complications28 days after surgeryCorrelation between blood transfusion and postoperative pulmonary complications

Countries

China

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026