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Mulligan Mobilization in Rheumatoid Hand

Comparison of the Effects of Exercise and Protective Approach in the Rheumatoid Hand and Joint Mobilization Applications on Pain, Functional Status and Quality of Life

Status
Completed
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT05660629
Enrollment
21
Registered
2022-12-21
Start date
2023-10-30
Completion date
2024-12-12
Last updated
2024-12-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Rheumatoid Arthritis

Keywords

Mulligan Mobilization, Hand Rheumatoid Arthritis

Brief summary

The goal of this randomized-controlled study is to learn about the effectiveness of the Mulligan mobilization in rheumatoid hands. The main question it aims to answer are: -Does mulligan mobilization reduce effusion in wrist joints with rheumatoid arthritis? Participants will take Mulligan mobilization application and active ROM exercises for their hands. Researcher will compare treatments group ith sham mobilization.

Detailed description

Rheumatoid arthritis (RA) is a systemic disease that can lead to chronic pain, bone and soft tissue damage, and disability retirement. Alleviating pain and maintaining joint range of motion in RA are important for reducing disability. Joint mobilizations are manual therapy techniques used to increase range of motion and reduce pain. The aim of this study is to investigate the effects of rheumatoid hand exercise and protective approach and joint mobilization applications on pain, functional status and quality of life.

Interventions

OTHERMulligan Mobilization

Mobilization with movement (MWM) is the concurrent application of sustained accessory mobilization applied by a therapist and an active physiological movement to end range applied by the patient. Passive end-of-range overpressure, or stretching, is then delivered without pain as a barrier.

Sponsors

Kirsehir Ahi Evran Universitesi
Lead SponsorOTHER

Study design

Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
DOUBLE (Subject, Caregiver)

Eligibility

Sex/Gender
ALL
Age
30 Years to 65 Years
Healthy volunteers
No

Inclusion criteria

* Having been diagnosed with RAS according to ACR and EULAR criteria, * Being under the control of a physiatrist for at least 1 year, * Have not had any upper extremity surgery in the last 6 months * Have the cognitive capacity to understand commands, * Not to be involved in any other rehabilitation program or study,

Exclusion criteria

* Presence of soft tissue injury and chronic bone damage in the hand, * Presence of acute inflammation in any joint in the previous week, * Presence of a degenerative or non-degenerative neurological condition that causes a change in pain perception,

Design outcomes

Primary

MeasureTime frameDescription
Joint activity6 weeksPrimary outcomes included the automated quantification (Q) of joint activity using color Doppler pixel count calculations (% hyperemia/blood flow activity score within an inflamed joint: color Q-Doppler MCP/region)
Amount of hypertrophia and effusion in wrist joints6 weeksSynovial fluid (area of hypertrophy and effusion, mm2: synovial fluid MCP/region)
Distance in wrist joints6 weeksthe radiographic distance (mm) between the MCP or interphalangeal bone space (joint space MCP/region)
DAS-286 weeksHigh disease activ ity \>5.1, low disease activity ≤ 3.2, remission ≤ 2.6

Secondary

MeasureTime frameDescription
Determining the state of pain after treatment6 weeksPain will be assessed using the Mcgill-Melzack Pain Questionnaire
Physical, social, and emotional well-being in RA6 weeksArthritis Impact Measurement Scales (AIMS)
Grip force6 weeksHand grip strength will be measured with a pinch meter and a dynamometer
Range of Motion6 weeksRange of Motion will be measured with goniometer
Post-treatment status of disease-related quality of life6 weeksQuality of life was assessed using the Rheumatoid Arthritis Quality of Life (RAQoL).

Countries

Turkey (Türkiye)

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026