Cardiac Rehabilitation, Chronic Heart Failure
Conditions
Brief summary
The aim of this study is to investigate the effect of high-intensity interval training and moderate intensity continuous training on cardiopulmonary functions in chronic heart failure.
Detailed description
enroll chronic heart failure patients into 3 randomized controlled group * high intensity interval training * moderate intensity continous training * control perform cardica rehab for 12 weeks, compare primary and secondary endpoints between baseline and 12 weeks results
Interventions
BEHAVIORALCardiac rehabilitation comprised aerobic exercise on a treadmill accompanied by an electrocardiogram monitoring device and a blood pressure monitor
aerobic exercise on a treadmill (T7M, Motus, Paju, South Korea) accompanied by an electrocardiogram monitoring device (Q-Tel Rehabilitation Management System, Mortara Inc., Milwaukee, WI, USA) and a blood pressure monitor
Sponsors
Inha University Hospital
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
QUADRUPLE (Subject, Caregiver, Investigator, Outcomes Assessor)
Eligibility
Sex/Gender
ALL
Age
30 Years to 70 Years
Healthy volunteers
No
Inclusion criteria
* medically stable chronic heart failure * NYHA II-III * can perform cardiopulmonary exercise test * after 3months with proper medication * age 30 to 70 * ejection fraction\< 40%
Exclusion criteria
* contraindication to cardiopulmonary exercise test * musculoskeletal problem who cannot perform cardiopulmonary exercise test * cognition deficit who cannot understand directions * severe medial illness
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Maximal or peak oxygen consumption (VO2max or VO2peak, same meaning) (kg/ml/min) | compare baseline data with 12 weeks rehabilitation data | at the end of training, from baseline to 12 weeks |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| 6minute walk test (meter) | compare baseline data with 12 weeks rehabilitation data | — |
| maximal heart rate (bpm) | compare baseline data with 12 weeks rehabilitation data | — |
| systolic blood pressure (mmHg) | compare baseline data with 12 weeks rehabilitation data | — |
| diastolic blood pressure (mmHg) | compare baseline data with 12 weeks rehabilitation data | — |
| resting heart rate (bpm) | compare baseline data with 12 weeks rehabilitation data | — |
| Anaerobic threshold (kg/ml/min) | compare baseline data with 12 weeks rehabilitation data | The anaerobic threshold is the highest exercise intensity that you can sustain for a prolonged period without lactate substantially building up in your blood. |
| depression scale by Patient Health Questionnaire | compare baseline data with 12 weeks rehabilitation data | Patient Health Questionnaire (PHQ; range, 0-27; higher score = severe depression; cut-off score of 5 for minimal depression) |
| anxiety scale by Generalized Anxiety Disorder Scale | compare baseline data with 12 weeks rehabilitation data | Generalized Anxiety Disorder Scale (GAD; range, 0-21; higher score = severe anxiety; cut-off score of 5 for mild anxiety) |
| fatigue scale by fatigue severity scale | compare baseline data with 12 weeks rehabilitation data | fatigue severity scale (FSS; range, 9-63; higher score = severe fatigue; cut-off score of 4 for fatigue) |
| Quality of Life (QoL) questionnaire (MacNew) | compare baseline data with 12 weeks rehabilitation data | MacNew QoL questionnaire is a measurement tool for patients with cardiac disease that measures physical, emotional, and social functional levels to provide overall QoL. |
| diastolic blood presure (mmHg) | compare baseline data with 12 weeks rehabilitation data | — |
Countries
South Korea
Contacts
Primary ContactKyung-Lim Joa, M.D.
Outcome results
None listed