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Education Time Influence on Exercise-Induced Hypoalgesia

Education Time Influence on Exercise-Induced Hypoalgesia

Status
Completed
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT05658224
Enrollment
10
Registered
2022-12-20
Start date
2022-11-01
Completion date
2023-05-01
Last updated
2025-01-09

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Exercise

Keywords

Exercise induced hypoalgesia, Education

Brief summary

We will investigate the effects of the length of education on exercise-induced hypoalgesia (EIH). Two previous studies have shown that positive education about the effects of exercise and the phenomena of EIH produce enhancements to EIH response (having decreased reports of pain with exercise). These previous studies used different amounts of education time, this study will compare directly if the length of education time varies the effects on EIH.

Detailed description

The use of fliers will be posted on USD campus explaining study and the need for volunteers. Potential volunteers will contact study personal listed on the flier to set up potential time for study enrollment. When the prospective participant arrives, they will be provided a hard copy of informed consent and study personnel will be available to answer questions. If the participant consents and signs, they will then be screened to ensure inclusion/exclusion by answering screening questions. Once they have consented and met study inclusion/exclusion the participants will then be randomized into 1 of 2 groups by picking a number out of an envelope. Group 1 will receive a more extensive education session (10-15 min) on the benefits of exercise and EIH. Group 2 will receive a brief education session (1 minute) on the benefits of exercise and EIH. Next participants will complete basic demographic information: age, gender, history of injuries, athletic participation history, and Knowledge and Beliefs about Exercise and Pain Questionnaire (questions 1 -4). Then they will be introduced and tested for pain pressure threshold (PPT). This standard measurement assesses the threshold when a pressure applied to the body passes from pressure to pain. A PPT algometer with a 1 cm tip is used to apply pressure to a body part slowly. When the participant first feels the sensation of pain, the pressure being applied is stopped and the amount of force is recorded as the individual's PPT. The participant will initially be introduced to the testing at the web space of the thumb and index finger on their dominant hand, this is done 3 times with minimum 15 seconds between each measurement and the average of the 3 measurements is used. Participants then will receive the education about EIH depending on their group allocation last 1 minute or 10-15 minutes. After the education, the participants will be asked question #5 on the Knowledge and Beliefs about exercise and pain questionnaire. Both groups will be shown a picture of the exercise (wall squat) that they will perform and provided instruction on the exercise before they begin. The wall squat exercise will consist of standing upright with their back against the wall with feet 45 cm from the wall, feet parallel and shoulder width apart, and hands at their side. They will slide down the wall bending at the hips and knees, keeping their back against the wall and feet in place until their knee joint angle reaches 100 degrees of flexion measured by the study personnel. All participants are asked to maintain the position for 3 minutes or until fatigued and need to stop. Prior to beginning the wall squat exercise, participants are asked to rate the intensity of pain in their legs using the Numeric Rating Scale (NRS=0-10, 0=no pain, 10=worst imaginable pain). Pain Pressure Threshold will be measured on the dominant quadriceps muscle and the non-dominate upper trapezius muscle. During the exercise, the NRS and category-ration scale of Rating of Perceived Exertion (CR 10, 0=nothing at all, 10=extremely strong) will be measured while performing the exercise at 1 minute, 2 minutes, and 3 minutes. Immediately post-exercise, Pain Pressure Threshold will be measured again on the dominant quadriceps muscle and the non-dominate upper trapezius muscle. The participants will also be asked to assess exercise expectations on EIH immediately post-exercise.

Interventions

BEHAVIORALEducation on effects of Exercise-induced hypoalgesia from exercise

Educational session with participants

Sponsors

University of South Dakota
Lead SponsorOTHER

Study design

Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
BASIC_SCIENCE
Masking
DOUBLE (Subject, Outcomes Assessor)

Masking description

Participants will be randomized into 1 of 2 groups. Outcome assessor will not be informed of participant grouping.

Eligibility

Sex/Gender
ALL
Age
18 Years to 64 Years
Healthy volunteers
Yes

Inclusion criteria

* Able to read and understand English, * Refrained from alcohol, pain medication, and vigorous exercise for the past 24 hours, * No history of chronic pain (pain \> 3 months), or current pain/injury that would prevent the ability to do exercise.

Exclusion criteria

* unable to meet screening questions for PAR-Q+ for safe exercise

Design outcomes

Primary

MeasureTime frameDescription
Pain Pressure Threshold3 minutes post exercise on Day following educational session and exerciseMeasurement in kg/cm2, higher score is better outcome

Secondary

MeasureTime frameDescription
Knowledge and Beliefs About Exercise and Pain Questionnaire3 minutes post exercise on Day following educational session and exercisepaper questionnaire on Likert scale 1 strongly disagree, 5 strongly agree. higher number indicates more knowledge.

Countries

United States

Participant flow

Participants by arm

ArmCount
Short Education
Individuals receiving a short (1-minute) educational session on exercise-induced hypoalgesia Education on effects of Exercise-induced hypoalgesia from exercise: Educational session with participants
5
Long Education
Individuals receiving long (10-15 minutes) educational session on exercise-induced hypoalgesia Education on effects of Exercise-induced hypoalgesia from exercise: Educational session with participants
5
Total10

Baseline characteristics

CharacteristicShort EducationTotalLong Education
Age, Continuous23.8 years
STANDARD_DEVIATION 0.837
24 years
STANDARD_DEVIATION 0.775
24.2 years
STANDARD_DEVIATION 0.837
Race (NIH/OMB)
American Indian or Alaska Native
0 Participants0 Participants0 Participants
Race (NIH/OMB)
Asian
0 Participants0 Participants0 Participants
Race (NIH/OMB)
Black or African American
0 Participants0 Participants0 Participants
Race (NIH/OMB)
More than one race
0 Participants0 Participants0 Participants
Race (NIH/OMB)
Native Hawaiian or Other Pacific Islander
0 Participants0 Participants0 Participants
Race (NIH/OMB)
Unknown or Not Reported
0 Participants0 Participants0 Participants
Race (NIH/OMB)
White
5 Participants10 Participants5 Participants
Region of Enrollment
United States
5 participants10 participants5 participants
Sex: Female, Male
Female
4 Participants7 Participants3 Participants
Sex: Female, Male
Male
1 Participants3 Participants2 Participants

Adverse events

Event typeEG000
affected / at risk
EG001
affected / at risk
deaths
Total, all-cause mortality
0 / 50 / 5
other
Total, other adverse events
0 / 50 / 5
serious
Total, serious adverse events
0 / 50 / 5

Outcome results

Primary

Pain Pressure Threshold

Measurement in kg/cm2, higher score is better outcome

Time frame: 3 minutes post exercise on Day following educational session and exercise

ArmMeasureValue (MEAN)Dispersion
Short EducationPain Pressure Threshold0.72 kg/cm^2Standard Deviation 0.58
Long EducationPain Pressure Threshold1.13 kg/cm^2Standard Deviation 2.39
Secondary

Knowledge and Beliefs About Exercise and Pain Questionnaire

paper questionnaire on Likert scale 1 strongly disagree, 5 strongly agree. higher number indicates more knowledge.

Time frame: 3 minutes post exercise on Day following educational session and exercise

ArmMeasureValue (MEAN)Dispersion
Short EducationKnowledge and Beliefs About Exercise and Pain Questionnaire3.4 units on a scaleStandard Deviation 1.517
Long EducationKnowledge and Beliefs About Exercise and Pain Questionnaire3.2 units on a scaleStandard Deviation 0.837

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026