Antibacterial Effect of New Herbal Paste Used as an Intracanal Medication

Antibacterial Effect of New Herbal Paste Used as an Intracanal Medication in Necrotic Primary Molars, a Randomized Control Trial

Status

UNKNOWN

Phases

Phase 3

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT05657132

Enrollment

Registered

2022-12-20

Start date

2021-08-19

Completion date

2022-12-30

Last updated

2022-12-20

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Infection Primary

Keywords

infected primary molars, metapaste, herbal paste

Brief summary

studying the antibacterial effect of Cosuts paste as an intracanal medication against Enterococcus faecalis that present in necrotic primary teeth

Detailed description

The children were randomly divided into two groups (I, II) Group I (N=12): using Costus-based paste as an intracanal medicament. Group II (N= 12): Calcium hydroxide iodoform paste (Metapex) as an intracanal medicament. Procedure: Access opening was started. then a swab was taken from the distal root canal with a dry paper point and transferred to a sterile test tube. The canals were filled with an intracanal medication according to the patient group. In group I, the canals was filled with a previously prepared Costus-based paste for one week, and In Group II, the canals were filled with Meta paste for one week. After 1 week, the paste was washed away from the canals then another swab was taken from the distal canal by a dry paper point as done before preoperatively. The 2 swabs were transferred within 2 hours to the lab for bacterial culture and detection of enterococcus faecalis count.

Interventions

DRUGherbal intracanal medication paste

study the effect of costus herbal paste on enterococcus faecalis bacteria

DRUGMeta paste

compare the effect of Costus paste with meta paste in reducing the number of enterococcus faecalis

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

TREATMENT

Masking

SINGLE (Subject)

Masking description

blinded

Intervention model description

randomized control trial

Eligibility

Sex/Gender

ALL

Age

4 Years to 10 Years

Healthy volunteers

Yes

Inclusion criteria

* Patients with clinically and radiologically diagnosed infected primary teeth in their mandibular arch. * Teeth should be deeply carious, with a history of spontaneous pain and carious exposures with necrotic pulp was also be selected * radiographic evidence of adequate alveolar bone support, and absence of internal or external resorption. * tooth must be restorable.

Exclusion criteria

* vital tooth * Non restorable teeth

Design outcomes

Primary

Measure	Time frame	Description
Bacterial count	1 weak	Colony forming unit

Countries

Egypt

Contacts

Primary ContactGhada Salem, Ph.D

ghadamohamedalirana@hotmail.com+201005144561

Backup ContactMariem Elmansy

drmaryamelmansy@hotmail.com01223355029

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026