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Prospective Study and Analysis of Biomechanical Parameters of Human Movement Based on Disability Indicators in Older Adults

Study and Analysis of Biomechanical Parameters of Human Movement Based on Disability Indicators in Older Adults Based on a Multifactorial Analysis: a Prospective Cohort Study

Status
Completed
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT05656690
Acronym
MOBA-P
Enrollment
60
Registered
2022-12-19
Start date
2022-05-01
Completion date
2024-07-31
Last updated
2024-11-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Disability

Brief summary

Mobility loss in older people is caused by a variety of aging impairments in various body systems.The disability, which includes physical impairments and resulting activity limitations or participation restrictions, can arise acutely from a catastrophic illness or, more commonly, from subacute functional decline without a clear triggering event. Lower physical functioning was associated with higher healthcare utilization and expenditures, leading to a large burden on government-funded healthcare services. Early identification of mobility changes and intervening in them would likely be the most effective strategy to reduce the burden of disability in the population. Overall, there is a need to develop strategies to reduce disability among older adults in which kinetic and kinematic characteristics are used to predict disability status. Accordingly, the purpose of this prospective cohort is to identify biomechanical parameters, from the gait, sit-to-stand, timed up and go, stair ascend and descend, and quiet standing functional tasks, as predictors of changes in health and disability status in older adults. This research was funded by Fundação para a Ciência e Tecnologia (FCT), NORTE 2020, and European Social Fund of European Union, grant number 2020.05356.BD and through R&D Units funding (UIDB/05210/2020), Fundação para a Ciência e Tecnologia (FCT), Portugal and the European Union.

Interventions

Disability status assessed by functional measures

Sponsors

Center for Rehabilitation Research - Polytechnic Institute of Porto (IPP)
CollaboratorUNKNOWN
Universidade do Porto
CollaboratorOTHER
School of Allied Health Sciences of Porto (ESTSP) - Polytechnic Institute of Porto (IPP)
CollaboratorOTHER
Polytechnic Institute of Porto
Lead SponsorOTHER

Study design

Observational model
COHORT
Time perspective
PROSPECTIVE

Eligibility

Sex/Gender
ALL
Age
60 Years to No maximum
Healthy volunteers
Yes

Inclusion criteria

* older adults, 60 years or over; * community-dwelling; * able to perform the tasks (gait, sit-to-stand, climb and descend stairs) independently;

Exclusion criteria

* older adults who are institutionalized; * older adults who have established diagnosis of malignancy or terminal diseases with an anticipated survival of less than 1 year; * older adults who have stroke history, cerebral hemorrhage, head trauma, or Parkinson's disease; * older adults who have cognitive impairment, specifically Mini Mental StateExamination (Portuguese version) score of 22 for 0 to 2 years of literacy, 24 for 3 to6 years of literacy and 27 for more than 6 years of literacy (Morgado et al., 2009); * older adults who have rheumatic pathologies that interfere with the tasks performance; * older adults who have diabetic foot, lower limb fracture less than 6 weeks, or other related conditions; * older adults who have unstable cardiovascular disease, liver or renal function failure; * older adults who have a body mass index greater than or equal to 30 kg/m2; * older adults who vestibular and/or audition or vision impairments non corrected that influence the performance of tasks; * older adults who presence of symptoms at the time of evaluation that influences the participant performance of tasks.

Design outcomes

Primary

MeasureTime frameDescription
Waveform from total body energyAssessed once at study entryWaveform from total body energy measured in joules (J)
Waveform from full-body separate segment energyAssessed once at study entryWaveform from body segment energy un joules (J)
Waveform from full-body angular joint velocitiesAssessed once at study entryWaveform from angular joint velocities measured in degrees per second (°/s)
Waveform from lower limb joint momentsAssessed once at study entryWaveform from lower limb joint moments measured in Newton-meter (kgm²/s²)
Waveform from centre of mass displacementAssessed once at study entryWaveform from centre of mass displacement in m/s
Waveform from centre of pressure displacementAssessed once at study entryWaveform from centre of pressure displacement in m/s
Waveform from lower body joint forcesAssessed once at study entryWaveform from lower body joint forces measured in Newton (N)
Waveforms from full-body joint anglesAssessed once at study entry.Waveforms from full-body joint angles measured in degrees (°)
Waveform from lower body joint powerAssessed once at study entryWaveform from lower body joint power measured in Watts
International Physical Activity QuestionnaireAssessed at study entry and evaluated every three months until the end of 1 yearIPAQ is questionnaire to assess self-reported physical activity
Mini-Mental State Examination (MMSE)Assessed at study entry and evaluated every three months until the end of 1 yearMMSE provides a brief screening test that quantitatively assesses the severity of cognitive impairment and documents cognitive changes occurring over time
Barthel IndexAssessed at study entry and evaluated every three months until the end of 1 yearThe Barthel Index is an instrument that assesses the individual's level of independence for ten activities of daily living
Lawton and Brody Instrumental Activities of Daily Living ScaleAssessed at study entry and evaluated every three months until the end of 1 yearLawton and Brody Instrumental Activities of Daily Living Scale assess the instrumental ADLs necessary for living in the community
Number of health conditionsAssessed at study entry and evaluated every three months until the end of 1 yearTotal number and description of health conditions
Number of fallsAssessed at study entry and evaluated every three months until the end of 1 yearTotal number and description of ocurrences of falls

Countries

Portugal

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026