Meniscus Lesion
Conditions
Brief summary
The purpose was to assess knee function outcomes between early arthroscopic partial meniscectomy(APM) and delayed APM for patients with degenerative meniscus lesions(DMLs)
Detailed description
Whether early APM surgery or delayed APM surgery will more benefit for patients with DMLs. The study was to determine the early APM vs delayed APM effect on knee function outcomes for patients with DMLs for 1 year follow-up.
Interventions
PROCEDUREearly APM
early APM within 3 and 6 month knee pain symptoms
PROCEDUREdelayed APM
delayed APM within 6 and 12 month knee pain symptoms
Sponsors
Shenzhen People's Hospital
Study design
Allocation
NON_RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
DOUBLE (Investigator, Outcomes Assessor)
Eligibility
Sex/Gender
ALL
Age
35 Years to 70 Years
Healthy volunteers
No
Inclusion criteria
* • Clinical diagnosis of degenerative meniscus lesions based on knee MRI
Exclusion criteria
* • Must be able to have no acute knee injury such as car crash or acute sports injury; * Must be able to have no knee surgeries history; * Must be able to have no rheumatoid arthritis or serious knee osteoarthritis with deformity; * Must be able to have no contraindications to MRI; * Must be able to have no severe cardiopulmonary disease; * Must be able to have no musculoskeletal or neuromuscular impairments ; * Must be able to have good visual, hearing, or cognitive;
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| the Knee Injury and Osteoarthritis Outcome Score (KOOS) change | change from baseline up to 12 months | The Knee injury and Osteoarthritis Outcome Score (KOOS) holds five subscales including: Pain (9 items); other Symptoms (7 items); Activities of Daily Living (ADL, 17 items); Sport and Recreation function (Sport/Rec, 5 items); and knee-related Quality of Life (QoL, 4 items). Each subscale is scored separately from zero (extreme knee problems) to 100 (no knee problems) |
| International Knee Documentation Committee Subjective Knee Evaluation Form (IKDC Score) change | change from baseline up to 12 months | The International Knee Documentation Committee Subjective Knee Evaluation Form (IKDC) score questionnaire contains 18 items (7 items for symptoms, 1 item for sport activity, 9 items for daily activities, and 1 item for current knee function.) The total score is transformed to a value on a scale of 0 to 100, with 100 representing the highest knee function and 0 is the worst. |
| Kellgren-Lawrence (K/L) grade change | change from baseline up to 12 months | Kellgren-Lawrence (K/L) grade via X ray |
| the Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) change | change from baseline up to 12 months | Te WOMAC is a self assessed health status scale for patients consisting of 24 items in three subscales of pain (5 items), stiffness (2 items), and physical function (17 items). All items are scored from 0 (asymptomatic) to 4 (very severe), and the total score ranges from 0 to 96, with higher scores indicating more severe symptoms |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| KOOS pain score change | change from baseline up to 12 months | The minimum is 0 points, the maximum is 4 points, from extreme knee problems to no knee problems. After the score of each part is calculated separately, it is converted into a percentage score by the conversion formula. |
| KOOS knee related quality of life score change | change from baseline up to 12 months | The minimum is 0 points, the maximum is 4 points, from extreme knee problems to no knee problems. After the score of each part is calculated separately, it is converted into a percentage score by the conversion formula. |
| KOOS symptoms score change | change from baseline up to 12 months | The minimum is 0 points, the maximum is 4 points, from extreme knee problems to no knee problems. After the score of each part is calculated separately, it is converted into a percentage score by the conversion formula. |
| KOOS activities of daily living score change | change from baseline up to 12 months | The minimum is 0 points, the maximum is 4 points, from extreme knee problems to no knee problems. After the score of each part is calculated separately, it is converted into a percentage score by the conversion formula. |
| KOOS function in sport and recreation score change | change from baseline up to 12 months | The minimum is 0 points, the maximum is 4 points, from extreme knee problems to no knee problems. After the score of each part is calculated separately, it is converted into a percentage score by the conversion formula. |
Outcome results
None listed