Skip to content

Evaluation of Sun's Scoring System Use in Post-pancraticodoudenectomy Pancreatic Fistula

Evaluation of Sun's Scoring System Use in Post-pancraticodoudenectomy Pancreatic Fistula; an Observational Cohort Study.

Status
UNKNOWN
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT05654636
Enrollment
40
Registered
2022-12-16
Start date
2023-01-01
Completion date
2025-03-31
Last updated
2022-12-16

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Risk Scoring System for Prediction of Pancreatic Fistula Post PD

Brief summary

Evaluation of sun scoring system for predication of pancreatic fistula after Pancreaticoduodenectomy to facilitate timely intervention after Pancreaticoduodenectomy.

Detailed description

Pancreaticoduodenectomy is the only option curative intended in the treatment of resectable pancreatic ductal adenocarcinomas, duodenal carcinoma, ampullary carcinoma, lower common bile duct cholangiocarcinoma,. It is still associated with very high morbidity and mortality. \[1\]. Pancreatic cancer ranks as the seventh leading cause of cancer-related death worldwide, and the fourth among other cancers\[2,3\]. Pancreatic fistula(PF) is one of the most important complications after Pancreaticoduodenectomy, with an incidence of about 10% to 28%.\[4\].There are multiple risk factors for the predication of development of pancreatic fistula after pancreaticoduodenectomy which include soft gland texture, non-pancreatic cancer non-chronic pancreatitis pathology, small pancreatic duct diameter (\<3 mm), and high intraoperative blood loss (\>1000 mL) , excess intraoperative fluid administration and increased pancreatic parenchymal remnant volume \[5,6,7\]. Other reported risk factors as increased body mass index (BMI), poor preoperative nutrition, and male gender which preoperative may lead to pancreatic fistula \[8.9\]. Recent studies are deficient in evaluation and predication of pancreatic fistula . So the interest of our study to evaluate and predicate the risk factors and management of pancreatic fistula after Pancreaticoduodenectomy .

Interventions

None listed

Sponsors

Assiut University
Lead SponsorOTHER

Study design

Observational model
COHORT
Time perspective
PROSPECTIVE

Eligibility

Sex/Gender
ALL
Age
25 Years to 70 Years

Inclusion criteria

* All the cases indicated for Pancreaticoduedenectomy with : 1. age less than 70 years. 2. resectable tumour, 3. fitness patients

Exclusion criteria

* 1\_patients with jaundice with serum bilirubin above 200mml/dl. 2\_patients with bleeding tendency until corrected. 3\_patients with advanced and metastatic malignancy. 4\_patients with cardiopulmonary diseases.

Design outcomes

Primary

MeasureTime frameDescription
predication of pancreatic fistula after Pancreaticoduodenectomy to facilitate timely intervention after PancreaticoduodenectomyBaselineEarly prediction of pancreatic fistula post PD facilities threraputic intervention and life saving in some cases

Secondary

MeasureTime frameDescription
Reduce the morbidity and mortality and improve the quality after pancraticoduodenectomyBaselineManagement of pancreatic fistula post PD improve quality of life

Contacts

Primary ContactMahmoud Saber Mekhemer, Resident
mahmoud.saber.3291@gmail.com01141608732
Backup ContactSalah Ibrahim Mohamad, MD
salah.Ibrahim@med.au.edu.eg01061616104

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026