Nasal Surgery
Conditions
Keywords
general anesthesia, electroencephalogram, emergence agitation, sevoflurane
Brief summary
The purpose of the study is to evaluate the relationship between perioperative electroencephalogram and emergence agitation in the nasal surgery. Previous studies showed that low frequency band wave activity increased during emergence delirium in pediatric patients. It is still not enough to explain the relationship between emergence agitation and electroencephalogram in adults. Researchers will demonstrate the relationship between parameters related electroencephalogram and emergence agitation in adults undergoing nasal surgery.
Detailed description
Researchers use Sedline to perform perioperative EEG measurements of young adult patients undergoing nasal surgery under general anesthesia with sevoflurane. Emergence agitation occurrence and EEG patterns are observed. The researchers record the patient's sex, type of surgery, pre-education on emergence agitation, preoperative hospital anxiety and depression scale (HADS), postoperative pain, amount of analgesics administered in the surgery/recovery room, and PACU time. Investigators check the correlation between EEG and perioperative variables. Investigators also compare EEG and perioperative variables for those who were given an explanation of emergence agitation and those who were not.
Interventions
OTHERNasal surgery
Nasal surgery under general anesthesia using inhalational agent (sevoflurane)
Sponsors
Gangnam Severance Hospital
Study design
Observational model
COHORT
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
19 Years to 55 Years
Healthy volunteers
No
Inclusion criteria
* Adult patients aged 19-55 years who are undergoing nasal surgery under general anesthesia using inhalational agent
Exclusion criteria
* CNS disease (ex.dementia, stroke, brain tumor, psychological disorder..) * unable to communicate * general anesthesia history within 6 months * disagree to participate in study
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| EEG band relative power measured in the frontal lobe | From the cessation of sevoflurane inhalation to the extubation of tracheal tubes | relative power of each brain waves : Original frontal EEG waves using 4 channel sedline (Masimo, Irvine, CA, USA) sensor will processed by FFT(fast Fourier transform). Each band is as follows.: Delta: 1-4 Hz Theta: 4-8 Hz Alpha: 8-13 Hz Beta: 13-30 Hz. |
| occurrence of emergence agitation | From the cessation of sevoflurane inhalation to transfer to the recovery room | Emergence agitation occurrence : RASS(Richmond Agitation Sedation Score) is 10 scaled (-5\ +4) score to assess sedation/agitation level; 0 is a calm state, and a value less than 0 means a sedation state. |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| HADS (Hospital Anxiety and Depression Scale) | 1 day before surgery (after admission) | A self-assessment scale, brief, clinically useful measure of anxiety and depression symptoms. It can be used to diagnose depression in people with significant physical ill-health. |
| VAS (Visual Analogue Scale) | during 30 minutes after PACU admission | Using a ruler, it is 11 scaled (0-10) score to assess pain. |
| Effect of preoperative education on emergence agitation | up to 6 months after completion of the study | Investigate the relationship between preoperative emergence agitation explanation and occurrence of emergence agitation |
Countries
South Korea
Contacts
Primary ContactYoung Song
Backup ContactJiwon Lee
Outcome results
None listed