Coronary Heart Disease, ST Elevation Myocardial Infarction
Conditions
Brief summary
The goal of this observational study is to learn about in STEMI with Primary PCI Patients. The main questions it aims to answer are: * To determine the value of AMR in predicting the long-term clinical prognosis of patients with STEMI after PPCI, and to find the best cut-off value. * Analyze the factors of PPCI affecting AMR and explore the effective measures of PPCI microcirculation protection. Radiographic images of STEMI receiving primary PCI treatment in several chest pain centers in China will be included. The last image of the infarct-related vessel will be used as a target to calculate its AMR. The relationship between AMR and long-term clinical prognosis was analyzed.
Interventions
None listed
Sponsors
Henan Institute of Cardiovascular Epidemiology
Study design
Observational model
COHORT
Time perspective
RETROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* Aged 18 or older * Type 1 myocardial infarction * Receive PPCI
Exclusion criteria
* Failed to identify culprit vessels. * Structural heart disease with moderate to severe aortic valve or mitral regurgitation and or stenosis that may affect cardiac function * Dialysis patients with severe renal insufficiency * Severe and uncontrollable arrhythmia * Complicated with dilated cardiomyopathy * Unable to tolerate dual antiplatelet therapy * Severe and uncontrollable anemia * Hyperthyroidism * TIMI blood flow 0-1 grade after PPCI
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| MACEs | 12 months | cardiac death, hospitalization for heart failure, target vessel revascularization，non-fatal MI |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| cardiac death | 12 months | All cause deaths will be considered cardiac unless a definite noncardiac cause can be established. |
| hospitalization for heart failure | 12 months | Hospitalization for heart failure was defined as admission because of new or deteriorating signs and symptoms of heart failure combined with the findings of noninvasive imaging or elevated B-type natriuretic peptide(BNP) and/or N-terminal pro-BNP concentration, and a discharge diagnosis of congestive heart failure. |
| target lesion revascularization | 12 months | The following 3 conditions need to be met at the same time: 1. The new stenosis that developed within previously treated coronary segments and within 5 mm of their borders; 2. The new stenosis resulted in the vessel μQFR ≤ 0.80; 3. The patient subsequently underwent repeat PCI or coronary artery bypass grafting (CABG). |
| Repeated myocardial infarction | 12 months | Repeated myocardial infarction |
Countries
China
Outcome results
None listed