Bladder Dysfunction, BPH With Urinary Obstruction, Overactive Bladder
Conditions
Keywords
Detrusor Pressure, Bladder Compliance, Ultrasound, Ultrasound Vibrometery
Brief summary
The purpose of this study is to test a new ultrasound method called Quantitative Ultrasound Bladder Vibrometry to detect abnormal bladder function.
Detailed description
The purpose of this study is to evaluate the effectiveness of quantitative ultrasound bladder vibrometry (QUBV) as a noninvasive tool for detrusor overactivity assessment and for benign prostatic hyperplasia (BPH) treatment selection. Participants in this study will have a QUBV ultrasound performed at the same time as a urodynamic study that had been ordered as part of their regular clinical care.
Interventions
None listed
Sponsors
Mayo Clinic
Study design
Observational model
CASE_ONLY
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to 90 Years
Healthy volunteers
No
Inclusion criteria
* Aim1: Age \>18 scheduled to undergo UDS for their clinical care for one of the included diagnoses. -Aim2: Inclusions: Age \>45 scheduled to undergo selective photovaporization of the prostate.
Exclusion criteria
* Aim1:Obesity (BMI \>35kg/m2), known neurologic disease impacting bladder function (e.g. spinal cord injury, multiple sclerosis, Parkinson's, prior cerebrovascular accident), previous pelvic radiation therapy, previous radical pelvic surgery (such as for uterine or colorectal cancer), prior bladder surgery (including prostate resection), and pregnant or breast-feeding women. * Aim2:Obesity (BMI \>35kg/m2), known neurologic disease impacting bladder function (e.g. spinal cord injury, multiple sclerosis, Parkinson's, prior cerebrovascular accident), previous pelvic radiation therapy, previous radical pelvic surgery (such as colorectal cancer).
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Accuracy of quantitative ultrasound vibrometry for measuring detrusor pressure | time Frame: Up to study completion, an average of 1 year | Will be reported including 95% confidence intervals derived from the cross-validation procedure. |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Accuracy of quantitative ultrasound vibrometry for selecting BPH patients for de-obstructive surgery | time Frame: Up to study completion, an average of 1 year | Will be reported including 95% confidence intervals derived from the cross-validation |
Countries
United States
Contacts
CONTACTAzra Alizad, MD
CONTACTKathryn (Katie) Barthels
PRINCIPAL_INVESTIGATORAzra Alizad, MD
Mayo Clinic
Outcome results
None listed