Colon Adenoma
Conditions
Keywords
Adenoma detection rate, colonoscopy
Brief summary
The incidence of colorectal cancer in China is increasing year by year. Studies have shown that colorectal cancer is more common in the left colon，especially in the China. Our previous study also showed a higher rate of missed adenoma in the left colon than the right colon during colonoscopy. Additionally, prolonging withdrawal time could only improve the ADR of right colon, but had limited effect on the ADR of left colon in our previous research. Our aim is to evaluate the effect of a second forward view examination of the left colon on the detection of adenoma detection during colonoscopy.
Interventions
BEHAVIORALre-examination
During colonoscopy, the left colon was examined a second time in the forward view.
BEHAVIORALextended withdraw time
During colonoscopy, the left colon was examined with double basic withdrawal time in the forward view.
Sponsors
No.85 Hospital, Changning, Shanghai, China
Shanxi Provincial People's Hospital
The General Hospital of Eastern Theater Command
The Sixth Affiliated Hospital of Guangzhou Medical University
Fudan University
Kunshan Hospital of Traditional Chinese Medicine
Ningjin County Hospital
Qinghai People's Hospital
The First Affiliated Hospital of Yangtze University
Qujing NO.1 Hospital
Jiangxi Provincial People's Hopital
Yueyang Central Hospital
The First Affiliated Hospital of Hunan University of Traditional Chinese Medicine
The First People's Hospital of Changde City
Xuzhou Central Hospital
Wenzhou Central Hospital
Anhui Provincial Hospital
Jiangsu Provincial People's Hospital
Xiangya Hospital of Central South University
Changhai Hospital
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
DIAGNOSTIC
Masking
SINGLE (Subject)
Eligibility
Sex/Gender
ALL
Age
45 Years to 85 Years
Healthy volunteers
No
Inclusion criteria
* Patients whose age are between 40-75, or aged 76-85 depending on his condition * Patients who have indications for screening * Patients who have signed inform consent form.
Exclusion criteria
* Patients who have undergone colonic resection * Patients with alarming signs and symptoms of colorectal cancer: hematochezia, melena, anemia, weight loss, abdominal mass, positive digital rectal examination * Patients with abnormal blood coagulation or taking antiplatelets or anticoagulants within 7 days before colonoscopy * Patients with inflammatory bowel diseases * Patients with a history of abdominal surgery, or highly suspected or confirmed colorectal cancers by radiographic and laboratory tests Patients with hereditary colorectal cancer syndrome (including familial adenomatous polyposis). * Patients with pregnancy, severe chronic cardiopulmonary and renal disease. * Patients with failed cecal intubation * Patients with poor BPQ that necessitated a second bowel preparation * Patients with therapeutic colonoscopy for existing lesions * Patients refusing to participate or to provide informed consent
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Left colon adenoma detection rate (LCADR) | 60 minutes | LCADR is the number of patients with at least one adenoma in the left colon, divided by the total number of patients. |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| adenoma detection rate(ADR) | 60 minutes | ADR is the number of patients with at least one adenoma, divided by the total number of patients. |
| left colon adenomas per colonoscopy (LCAPC) | 60 minutes | LCAPC was calculated as the number of adenomas detected during in left colon colonoscopy withdraw divided by the number of colonoscopies. |
Countries
China
Contacts
Primary ContactZhaoshen Li, MD
Backup ContactYu Bai, MD
Outcome results
None listed