How Important Are Hematological Parameters in the Prognosis of Severe Covid-19 Patients?

Department of Infectious Disease and Clinical Microbiology

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT05650944

Enrollment

125

Registered

2022-12-14

Start date

2020-03-01

Completion date

2022-09-30

Last updated

2022-12-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

COVID-19

Keywords

Hemogram, NLR, MPV/PLT, MPV/PCT

Brief summary

It is aimed to reveal the treatment and prognostic values by evaluating the differences in hematological parameters and indices, especially in dead Covid-19 cases. Material Method: It is planned to retrospectively examine the hemogram parameters of 125 male, 44 female and 169 critical Covid-19 patients hospitalized between 01.03.2020 and 31.12.2021. Subjects were divided into 2 groups as deceased (77) and living (92) patients according to demographic data such as age and gender. Statistical evaluation: All analyzes were SPSS 25.0, Kolmogorov Smirnov test was used to determine distribution, median and interquartile range (Tukey's Hinges Percentile) were used to summarize variables. The differences between the Independent-Samples Mann Whitney U Test and the data of the patient groups and the optimal cut-off values, sensitivity and specificity values will be determined by ROC analysis. It will be considered statistically significant when the p value is below 0.05 (with the two-tailed test)

Detailed description

The aim of this study is to examine the effectiveness of routine laboratory complete blood count parameters and rates as diagnostic and prognostic criteria in severe COVID-19.

Interventions

DIAGNOSTIC_TESTHemogram

Sysmex XN-1000 hematological analyzer

Study design

Observational model

CASE_CONTROL

Time perspective

RETROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Healthy volunteers

Inclusion criteria

1. Patients over the age of 18 2. Critical patients taken to intensive care 3. The length of stay in the ICU is more than 24 hours

Exclusion criteria

1\) Patients under 18 years of age (2) Patients with hematological malignancies (3) The length of stay in the ICU is less than 24 hours.

Design outcomes

Primary

Measure	Time frame	Description
Hematological parameters in the prognosis of severe Covid-19 patients.	2020-2021	Hemogram values of the deceased and surviving patients participating in the study were compared.

Countries

Turkey (Türkiye)

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026