Periodontitis
Conditions
Keywords
Periodontitis, Re-evaluation, Non-surgical periodontal treatment
Brief summary
Re-evaluation after non-surgical periodontal treatment remains an integral part of comprehensive periodontal therapy. This re-evaluation determines if a patient is in need either of surgical periodontal therapy or a personalized program of supportive periodontal treatment. However important, this time point is yet to be determined.This interventional study aims to clarify which is the best time to re-evaluate the therapeutic result after non-surgical periodontal treatment.
Detailed description
This randomized clinical trial aims to clarify which is the best time to re-evaluate the therapeutic result after non-surgical periodontal treatment. For this purpose the participants will be recruited among people who come to the Periodontal Department of 251 Hellenic Air Force Hospital for periodontal treatment. Each participant is going to submit informed consent in order to be included in the study. Patients with the diagnosis of Periodontitis will be submitted to non-surgical periodontal treatment with ultrasonic and manual scalers within two sessions, under local anaesthesia. The result of the treatment is going to be evaluated at 6, 12 and 24 weeks after treatment completion.
Interventions
PROCEDUREPeriodontal treatment
Non-surgical periodontal treatment
Sponsors
251 Hellenic Air Force & VA General Hospital
Study design
Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
DIAGNOSTIC
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
Yes
Inclusion criteria
* Systematically healthy adults * Informed consent form completion * Periodontitis Diagnosis * Patients not having received periodontal treatment since 12 months before
Exclusion criteria
* Medical History that interferes with wound healing * Antibiotic and anti-inflammatory drugs intake * Medication that induces gingival enlargement * Pregnancy/ Lactation
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Probing Pocket Depth 0 | Baseline | The distance between the gingival margin and the base of the sulcus/pocket |
| Probing Pocket Depth 1 | 6 weeks after periodontal treatment | The distance between the gingival margin and the base of the sulcus/pocket |
| Probing Pocket Depth 2 | 12 weeks after periodontal treatment | The distance between the gingival margin and the base of the sulcus/pocket |
| Probing Pocket Depth 3 | 24 weeks after periodontal treatment | The distance between the gingival margin and the base of the sulcus/pocket |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Furcation involvement | Baseline, 6, 12, 24 weeks after treatment | Presence or absence of furcation involvement and degree of furcation defect |
| Clinical attachment level | Baseline, 6, 12, 24 weeks after treatment | The distance between cementoenamel junction and the base of the sulcus/pocket |
| Oral Health Impact Profile (OHIP)-14 Questionnaire | Baseline, 6, 12, 24 weeks after treatment | Questionnaire |
| matrix metalloproteinase | Baseline, 6, 12, 24 weeks after treatment | matrix metalloproteinase 8 levels in whole saliva |
| Plaque Index | Baseline, 6, 12, 24 weeks after treatment | Number of sites with presence of dental plaque/ total number of sites |
| Bleeding on Probing | Baseline, 6, 12, 24 weeks after treatment | Number of sites with presence of bleeding/total number of sites |
| Tooth Mobility | Baseline, 6, 12, 24 weeks after treatment | degree of tooth mobility |
Contacts
Primary ContactGeorgia Malamoudi, DDS,MSc
Backup ContactGeorge Koukos, DDS,PhD
Outcome results
None listed