Atherosclerosis, Cardiovascular Diseases, HIV, Human Immunodeficiency Virus
Conditions
Brief summary
The overall objective is to evaluate the efficacy of educational text messages to reduce cardiovascular risk among persons living with HIV (PLWH).
Interventions
BEHAVIORALDigital Educational Messaging
Education via mobile phone text messages for up to 6 months.
Sponsors
National Heart, Lung, and Blood Institute (NHLBI)
University of California, San Francisco
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
PREVENTION
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
40 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* HIV positive * At least 40 years of age * English-speaking
Exclusion criteria
* Existing clinical atherosclerotic cardiovascular disease (ASCVD) * Pregnant * Unwilling/unable to provide informed consent * Does not own a smartphone
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Proportion of participants with controlled blood pressure | 6 months | Proportion of participants with blood pressure \< 130/80 mmHg as recorded in the electronic health record (EHR). |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Systolic blood pressure | 6 months | Evaluated using EHR data. |
| Cholesterol | 6 months | Non-HDL cholesterol, total cholesterol, LDL cholesterol (in mg/dL), as evaluated using EHR data. |
| Physical activity | 6 months | Minutes/week, measured via self-report using the International Physical Activity Questionnaire (IPAQ). |
| Number of cardiovascular risk factors controlled | 6 months | Total of 8 risk factors: diet, physical activity, nicotine exposure, sleep health, body mass index, blood lipids, blood glucose, blood pressure. Risk factors will be assessed using self-report and EHR data. Risk factor control will be defined based on the American Heart Association's (AHA) Life's Essential 8. |
| Self-perceived cardiovascular risk | 6 months | Measured by self-report using questions adapted from the patient and provider assessment of lipid management (PALM) registry. |
| Proportion of current smokers | 6 months | Measured via self-report. |
| Blood sugar control | 6 months | Evaluated using EHR data on hemoglobin A1c and fasting blood glucose. Blood sugar control will be defined based on the AHA's Life's Essential 8 definitions. |
| Body mass index | 6 months | Evaluated in kg/m2 using EHR data. |
| Proportion of patients on guideline-based therapy | 6 months | Proportion of patients on anti-hypertensive medications, statins, and aspirin, among those who meet criteria for therapy based on American Heart Association / American College of Cardiology (AHA/ACC) guidelines. |
| Mediterranean diet | 6 months | Measured using the Mediterranean Eating Pattern for Americans (MEPA) tool, as scored by AHA's Life's Essential 8. Score ranges 0-16, with higher scores representing better outcomes. |
Countries
United States
Contacts
Primary ContactMegan McLaughlin, MD, MPH
Outcome results
None listed