Caffeine and Endurance Performance
Conditions
Brief summary
A study to test the hypothesis that a combined peat and apple extract will increase blood and muscle ATP, which will increase cycling performance
Interventions
DIETARY_SUPPLEMENTElevATP supplement
ElevATP supplement containing apple and ancient peat extract
DIETARY_SUPPLEMENTPlacebo
Maltodextrin placebo
Sponsors
VDF FutureCeuticals Inc.
University of Exeter
Study design
Allocation
RANDOMIZED
Intervention model
CROSSOVER
Primary purpose
BASIC_SCIENCE
Masking
DOUBLE (Subject, Investigator)
Eligibility
Sex/Gender
MALE
Age
18 Years to 40 Years
Healthy volunteers
Yes
Inclusion criteria
* Age 18 - 40 * Healthy * Recreationally active (i.e. Participants will be deemed as too trained if they are defined as participating in structured resistance exercise 3 or more times per week for \>6 months or participating in structured endurance exercise for \>6h per week for \>6 months. Participants will be defined as too sedentary if they do not exceed the governments guidelines of 150 / 75 min per week of light / heavy exercise.)
Exclusion criteria
* Allergy to Lidocaine * Any diagnosed metabolic health condition * Pregnant * Non-habitual caffeine intake * Smoker * Diagnosed Cardiovascular disease * Beta-Blockers * Recent history of musculoskeletal injury
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Muscle ATP concentration | 4 hours | Concentration of ATP in skeletal muscle tissue (mmol/kg dry weight) |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Total work performed during exercise | 2 hours | Work performed during glycogen depleting exercise on a cycle ergometer (J) |
| Blood ATP concentration | 4 hours | Concentration of ATP in blood (mmol/L) |
| Substrate oxidation | 1 hour | Substrate oxidation over 1 h steady state cycle (g/min) |
| Blood glucose concentration | 4 hours | Concentration of glucose in blood (mmol/L) |
| Muscle phosphocreatine concentration | 4 hours (mmol/kg dry weight) | Concentration of muscle metabolites |
| Muscle glycogen | 4 hours | Muscle glycogen concentration in skeletal muscle tissue (mmol/kg dry weight) |
| Muscle ADP concentration | 4 hours (mmol/kg dry weight) | Concentration of muscle metabolites |
| Muscle ATP concentration | 4 hours (mmol/kg dry weight) | Concentration of muscle metabolites |
| Muscle creatine concentration | 4 hours (mmol/kg dry weight) | Concentration of muscle metabolites |
| Blood lactate concentration | 4 hours | Concentration of lactate in blood (mmol/L) |
Countries
United Kingdom
Outcome results
None listed