Common Bile Duct Calculi
Conditions
Keywords
endoscopic retrograde cholangiopancreatography, endoscopic ultrasound, cholangitis
Brief summary
Retained CBD stone after ERCP is a common problem in clinical practice. This study aimed to evaluate the effect of saline irrigation of common bile duct after complete stone removal considered by ERCP in the reduction of residual CBD stone and the effect on clinical outcome.
Detailed description
This study aimed to evaluate the effect of saline irrigation of common bile duct after complete stone removal considered by ERCP in the reduction of residual CBD stone and the effect on clinical outcome. Patients with CBD stone who received endoscopic stone removal were included after complete stone clearance was seen on occluded cholangiogram. One arm received saline irrigation of CBD at least 50 ml until clear effluent seen and another arm as control. Both group received endoscopic ultrasound to evaluation for residual stone and followed up for complication and outcome.
Interventions
PROCEDURESaline irrigation group
Normal saline irrigation of common bile duct after complete stone removal
Sponsors
Department of Medical Services Ministry of Public Health of Thailand
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
SINGLE (Subject)
Masking description
The patients are blinded to the treatment
Intervention model description
Included patients are randomized to two group, study group and control group an followed up parallelly.
Eligibility
Sex/Gender
ALL
Age
18 Years to 80 Years
Healthy volunteers
No
Inclusion criteria
* Patients with common bile duct stone * Complete stone removal by endoscopy as seen in occluded cholangiogram
Exclusion criteria
* unstable vital sign * failed complete stone remval * assciated biliary malignancy or history of bile duct surgery * associated bile duct stricture or choledochal cyst * Toxic cholangitis * pregnancy or unable to give informed consent
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| prevalence of residual CBD stone | 1 day | Detected residual CBD stone by endoscoic ultrasound |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Complicaion and clinical outcome | 6 months | Complication associated with the procedure, hospital stay, and clinical outcome after the procedure |
| factors associated with retained CBD stone | 1 day | procedural and non-procedural factors related to retained CBD stone |
Countries
Thailand
Outcome results
None listed