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Fractal Analysis Method in Periodontal Disease

Evaluation of Trabecular Bone Changes in Individuals With Periodontal Disease Using Fractal Analysis

Status
Completed
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT05639582
Enrollment
200
Registered
2022-12-06
Start date
2020-11-05
Completion date
2021-11-05
Last updated
2022-12-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Periodontal Diseases

Keywords

Digital Radiography, Fractal Analysis, Periodontitis

Brief summary

In this study, the effects of periodontal disease on alveolar bone were investigated using fractal analysis method.

Detailed description

Background: It is very difficult to objectively evaluate the negative changes in bone structure due to periodontitis. The present study was aimed to evaluate the trabecular bone changes between healthy individuals and periodontitis patients by fractal dimension analysis on digital panoramic radiographs. Method: The study included 50 periodontally healthy individuals (control group), 50 individuals with Stage 1 periodontitis (S1-P group), 50 individuals with Stage 2 periodontitis (S2-P), and 50 individuals with Stage 3 periodontitis (S3-P), a total of 200 individuals were included. The fractal dimension (FD) value of the trabecular bone in the interproximal space between mandibular first molar and second premolar tooth roots was evaluated using Image J program. The mean fractal dimension values of the two regions were calculated by box counting method.

Interventions

fractal analysis is a method that numerically expresses bone changes.

Sponsors

Necmettin Erbakan University
Lead SponsorOTHER

Study design

Allocation
NON_RANDOMIZED
Intervention model
PARALLEL
Primary purpose
DIAGNOSTIC
Masking
NONE

Eligibility

Sex/Gender
ALL
Age
18 Years to 65 Years
Healthy volunteers
Yes

Inclusion criteria

* 18-65 years old * Getting a diagnosis of stage 1,2 and 3 periodontitis * Be diagnosed as periodontally healthy * Have no barriers to obtaining radiographs * Not having any systemic disease that may affect periodontal status * Not smoking and alcohol use * Volunteer to participate in the study

Exclusion criteria

* Those who use drugs that can affect bone metabolism * Radiographs with poor diagnostic quality * Root canal treatment or teeth with periapical lesions in the area of interest * Individuals who have suffered a fracture or trauma that affects the anatomy or integrity

Design outcomes

Primary

MeasureTime frameDescription
Evaluation of the effect of periodontal disease on alveolar bone by fractal analysisbaselineFractal dimension evaluation can give an objective result about the effect of periodontal disease on alveoler bone, since it shows changes in bone trabeculation numerically.

Secondary

MeasureTime frameDescription
Probing pocket depthbaselineProbing pocket depth(PPD) was measured for determining the severity of the disease and clinical outcome. High probing pocket depth shows more severe periodontal disease.
gingival indexbaselineThe differences in gingival index scores between periodontally healthy and periodontitis.The gingival index was recorded for determining and classifying gingival status. The Gingival İndex(GI) scores each site on a 0 to 3 scale with 0 being normal and 3 being severe inflammation characterized by edema, redness, swelling and spontaneous bleeding.
plaque indexbaselineThe differences in plaque index scores between periodontally healthy and periodontitis. Plaque index(PI) was recorded for determining and classifying oral hygiene status. The plaque index(PI) scores each site on a 0 to 3 scale with 0 being no plaque in the gingival area and 3 abundance of soft matter within the gingival pocket and/or on the gingival margin and adjacent tooth surface.

Countries

Turkey (Türkiye)

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026