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Petro-trigeminal Line and Petrous Apex Cephaloceles

The Petro-trigeminal Line: a Simple Radiological Marker for the Diagnosis of Cephaloceles of the Petrous Apex on MRI

Status
Completed
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT05639491
Acronym
APEX
Enrollment
209
Registered
2022-12-06
Start date
2020-09-18
Completion date
2020-11-18
Last updated
2023-11-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Petrous Apex Meningioma

Keywords

Petrous apex cephaloceles, Petrous apex, meckel's cave, cavum-trigeminale-cephaloceles, arachnoïd kyst, meningoceles, trigeminal nerves

Brief summary

cephaloceles are rare lesions of the petrous apex, inconsistently listed as meningoceles or arachnoid cysts. They're consistent with a herniation posterolateral of the Meckel cavum within the petrous apex. These lesions may be the cause of a symptomatology varied, or be discovered by chance in subjects who have not been asymptomatic. Currently, there is no evidence in the literature a simple, fast and reproducible radiological marker that allows for the diagnosis of cephaloceles of the petrous apex, in particular the small ones. The purpose of this study is to validate a radiological benchmark simple and reproducible, the trigeminal petrol line, in order to improve the diagnosis of petrous apex cephaloceles

Interventions

None listed

Sponsors

University Hospital, Strasbourg, France
Lead SponsorOTHER

Study design

Observational model
CASE_ONLY
Time perspective
RETROSPECTIVE

Eligibility

Sex/Gender
ALL
Age
18 Years to No maximum

Inclusion criteria

* Major subjects (≥18 years old) * patients who underwent an MRI with high resolution 3D T2 sequence between 01/01/2003 and 09/31/2020: * 200 patients consulting for ENT pathology such as vertigo * 9 patients presenting the radiological criteria in MRI of a cephalocele of the petrous apex according to the current data of the literature on a T2 3D HR sequence * \- Subject who has not expressed his opposition, after being informed, to the reuse of his data for the purposes of this research.

Exclusion criteria

* Subject who expressed their opposition to participating in the study * Kinetic Artifacts * Subject under guardianship or curatorship * Subject under safeguard of justice

Design outcomes

Primary

MeasureTime frameDescription
Validate a radiological landmark allowing MRI diagnosis cephaloceles of the petrous apexFiles analysed retrospectively from from January 01, 2003 to September 31, 2020 will be examinedThis mark corresponds to the projection of a line drawn on an axial section, in the plane of the posterior roots of the trigeminal nerves, between the anterior and external edges of the petrous apex along the petro-trigeminal angle on each side.

Countries

France

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026