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Built-in Calculator Optimizes Continuous Veno-venous Hemofiltration Prescription and Improves Therapeutic Quality in Critically-ill Acute Kidney Injury Patients

Built-in Calculator Optimizes Continuous Veno-venous Hemofiltration Prescription and Improves Therapeutic Quality in Critically-ill Acute Kidney Injury Patients

Status
Completed
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT05638711
Enrollment
1
Registered
2022-12-06
Start date
2019-01-01
Completion date
2022-08-01
Last updated
2022-12-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Built-in Culculator, CVVH, Filtration Fraction

Brief summary

The goal of this observational study is to compare in ICU patients received CVVH treatment. The main questions it aims to answer are: Control of Filtration fraction by built-in calculator * Reduced filter clotting and prolong filter lifespan * Improve patient mortality Participants will divided into before group and after group based on the day when built-in calculator for calculating Filtration fraction was utilized. Researchers will compare before group to see if there were differences in clotting events, filter downtime, filter lifespan, mortality, etc.

Detailed description

\# built-in calculator for calculating Filtration fraction * The calculator was built in prescription system since 2020/10/01 * providing tempt filtration fraction for operators to adjust CVVH dose * the protocol of patient care didn't change between before and after group.

Interventions

DEVICEBuilt-in calculator to calculate Filtration fraction

A calculator built in electronic CVVH prescription system to calculate Filtration fraction

Sponsors

Taipei Medical University
Lead SponsorOTHER

Study design

Observational model
COHORT
Time perspective
RETROSPECTIVE

Eligibility

Sex/Gender
ALL
Age
20 Years to No maximum
Healthy volunteers
No

Inclusion criteria

* ICU patients received CVVH during 2019\ 2021 (3 years) in our hospital

Exclusion criteria

* under age of 20, pregnant, or with HIV infection

Design outcomes

Primary

MeasureTime frameDescription
Mortality30 days, 60 days, through study completion, an average of 1.5 year mortality in ICU and in HospitalPatient death

Secondary

MeasureTime frameDescription
Filter lifespanthrough the complete treatment course hours, an average of 24 hoursaverage treatment time per filter
electrolytes_1the last record received before CVVH (in an average of 1 hour), the first record received CVVH after 24 hours, the first record received after CVVH (in an average of 1 hour)
electrolytes_2the last record received before CVVH (in an average of 1 hour), the first record received CVVH after 24 hours, the first record received after CVVH (in an average of 1 hour)K
electrolytes_3the last record received before CVVH (in an average of 1 hour), the first record received CVVH after 24 hours, the first record received after CVVH (in an average of 1 hour)Ca
electrolytes_4the last record received before CVVH (in an average of 1 hour), the first record received CVVH after 24 hours, the first record received after CVVH (in an average of 1 hour)P
Filter clotting eventsthrough the complete treatment course hours, an average of 24 hoursFilter clotting events
acid-base balance_2the last record received before CVVH (in an average of 1 hour before CVVH treatment), the first record received CVVH after 24 hours (in an average of 1 hour after CVVH treatment), the first record received after CVVH (in an average of 1 hour after CVVH)bicarbonate
Filter downtimethrough the complete treatment course hours, an average of 24 hoursdowntime between filter replacement
others_1the last record received before CVVH (in an average of 1 hour before CVVH treatment), the first record received CVVH after 24 hours (in an average of 1 hour after CVVH treatment), the first record received after CVVH (in an average of 1 hour after CVVH)body temperature
others_2the last record received before CVVH (in an average of 1 hour before CVVH treatment), the first record received CVVH after 24 hours (in an average of 1 hour after CVVH treatment), the first record received after CVVH (in an average of 1 hour after CVVH)platelet
acid-base balance_1the last record received before CVVH (in an average of 1 hour before CVVH treatment), the first record received CVVH after 24 hours (in an average of 1 hour after CVVH treatment), the first record received after CVVH (in an average of 1 hour after CVVH)pH

Countries

Taiwan

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026