Hydatidiform Mole
Conditions
Brief summary
The purpose of this study is to construct a cohort for the hydatidiform mole.
Detailed description
After being informed about the study and potential risks, all patients who meet the eligibility requirements will be enrolled.
Interventions
OTHERNo intervention
This is a prospective observational study with no intervention
Sponsors
Women's Hospital School Of Medicine Zhejiang University
Study design
Observational model
COHORT
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
FEMALE
Age
13 Years to 55 Years
Healthy volunteers
No
Inclusion criteria
1. Patients who are diagnosed with hydatidiform mole (including: complete hydatidiform mole/partial hydatidiform mole; one of twins with hydatidiform mole; ectopic pregnancy hydatidiform mole; macroscopic or microscopic hydatidiform changes indicating early complete or partial hydatidiform mole can not be excluded; atypical placental site nodule) for the first time; 2. Age 13-55 years old; 3. Obtain informed consent and sign an informed consent form
Exclusion criteria
1. Patients who are unable to cooperate with the investigation such as mental disorders or cognitive impairment 2. No histopathology diagnosis; 3. Patients with other malignancies
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Malignant trophoblastic tumor | 4.5 years | Patients with hydatidiform mole develop malignant trophoblastic tumor. The Federation of International of Gynecologists and Obstetricians criteria for diagnosis of postmolar gestational trophoblastic neoplasia were as follows: (1) when the plateau of human chorionic gonadotrophin (hCG) lasts for four measurements over a period of 3 weeks or longer; that is, days 1, 7, 14, 21; (2) when there is a rise in hCG for three consecutive weekly measurements over at least a period of 2 weeks or more; days 1, 7, 14; (3) If there is a histologic diagnosis of choriocarcinoma. |
Contacts
Primary ContactWeiguo Lv, PhD
Backup ContactXiao Li, PhD
Outcome results
None listed