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Assessment of Corneal Biomechanics With the Corvis ST in Different Age of Myopia With Orthokeratology

Assessment of Corneal Biomechanics With the Corvis ST in Different Age of Myopia With Orthokeratology

Status
Completed
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT05635526
Enrollment
134
Registered
2022-12-02
Start date
2020-06-01
Completion date
2022-10-01
Last updated
2022-12-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Myopia, Orthokeratology

Keywords

Myopia prevention and control, Orthokeratology, Dynamic corneal response

Brief summary

The present research focused on the effect of the age for the corneal biomechanics of low and moderate myopia patients after wearing orthokeratology (OK lens). According to age, the included cases were divided into 3 groups. Through the analysis of corneal biomechanical parameters, further learn the influence of OK lens on the patient cornea. It would help ophthalmologist and optometrist find out the potential issue and reach a better control result.

Detailed description

The present research focused on the effect of the age for the corneal biomechanics of low and moderate myopia patients after wearing orthokeratology (OK lens). According to age, the included cases were divided into 3 groups: Ⅰ (8-12 years old), Ⅱ (13-16 years old), Ⅲ (over 16 years old). The OK lenses used in the present study are of the same design (Euclid Systems Orthokeratology; Euclid System, Herndon, VA, USA). The base line (Day 0) and different follow-up time point (Day 1, Week 1, Week 2, Month 1, Month 3, and Month 6) of dynamic corneal response (DCR) (including 19 items) of the patients derived by Corvis ST were collected. The difference between before and after wearing OK Lens and the changes of parameters among the three groups were both analyzed. And the correlation between axis length (AL) and the 19 parameters also was analyzed. Through the analysis of corneal biomechanical parameters, further learn the influence of OK lens on the patient cornea. It would help ophthalmologist and optometrist find out the potential issue and reach a better control result.

Interventions

None listed

Sponsors

Tianjin Eye Hospital
Lead SponsorOTHER

Study design

Observational model
OTHER
Time perspective
RETROSPECTIVE

Eligibility

Sex/Gender
ALL
Age
8 Years to 40 Years
Healthy volunteers
No

Inclusion criteria

* age from 8 to 40 years old * spherical equivalent(SE) was range from -1.00D to -5.00D * conform to the standard of wearing orthokeratology lens

Exclusion criteria

* ocular diseases and systemic diseases * visual acuity was less than 20/20 * unable to follow visitors on time

Design outcomes

Primary

MeasureTime frameDescription
The change of dynamic corneal response (DCR)The change of baseline and 1 day, 1 week, 2 weeks, 1 month, 3 months, and 6 monthsThe axial length was measured by Corvis ST

Secondary

MeasureTime frameDescription
The change of axial lengthThe change of baseline and 6 monthsThe axial length was measured by AL-scan

Countries

China

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026