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Lung Ventilation and Perfusion in Different Phenotypes of Chronic Critical Illness With Prolonged Mechanical Ventilation

The Difference and Prognostic Significance of Lung Ventilation and Perfusion in Different Phenotypes of Chronic Critical Illness With Prolonged Mechanical Ventilation

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT05634135
Enrollment
103
Registered
2022-12-01
Start date
2022-07-31
Completion date
2025-02-17
Last updated
2024-12-30

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Prolonged Mechanical Ventilation

Keywords

Ventilation, mechanical ventilation, weaning, oxygen uptake

Brief summary

This project will conduct a series of analysis of physiological and clinical data on tracheostomy patients who receive prolonged mechanical ventilation, hoping to find out the different manifestations of patients through the investigation by a variety of physiologic measurements, so as to understand whether different types of patients phenotype to derive different clinical strategies for liberation of the mechanical ventilator.

Interventions

None listed

Sponsors

National Taiwan University Hospital
Lead SponsorOTHER

Study design

Observational model
COHORT
Time perspective
PROSPECTIVE

Eligibility

Sex/Gender
ALL
Age
20 Years to No maximum
Healthy volunteers
No

Inclusion criteria

* Patients with at least 10 days of mechanical ventilation at the intensive care unit of National Taiwan University Hospital and transferred to the Respiratory Care Center of National Taiwan University Hospital for weaning training * Patients who have undergone tracheostomy and still have a tracheotomy tube * Are at least 20 years old * Stable respiratory condition with inspired oxygen fraction not exceeding 50%

Exclusion criteria

* Hemodynamic instability or continuous use of vasopressors * Pregnancy

Design outcomes

Primary

MeasureTime frameDescription
Liberation from mechanical ventilation at discharge from the weaning unitFive daysAt least five consecutive days of free from mechanical ventilation ventilation

Countries

Taiwan

Contacts

Primary ContactJih-Shuin Jerng, MD, PhD
jsjerng@ntu.edu.tw+886-2-23123456

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026