Binocular Vision Disorder
Conditions
Keywords
binocular vision, accommodation, vergence, fMRI
Brief summary
Implantable collamer lens (ICL) is one of the most effective operation for high myopia. Due to refractive correction changed, and prism effect of the spectacle removed, in the early stage after ICL implantation, binocular function might be dysfunction, leading to asthenopia, blurred vision, double vision and so on. This study will recruit the high myopia subjects that scheduled for ICL implantation, purpose to investigate the binocular vision alternations and brain activation that impacted by ICL implantation.
Interventions
None listed
Sponsors
Zhongshan Ophthalmic Center, Sun Yat-sen University
Study design
Observational model
COHORT
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to 35 Years
Healthy volunteers
Yes
Inclusion criteria
* Age 18-35 * Spherical equivalent over -6.00DS, astigmatism within -2.00DC, anisometropia within -2.00DS * BCVA ≥ 0.8 * Plan to accept implantable collamer lens surgery * Near point of convergence within 10cm * Positive fusion vergence over 20pd
Exclusion criteria
* Stabismus * Previous ocular surgery or trauma * History of vision therapy * Monovision and nystagmus * Mental disease or craniocerebral trauma
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Changes of accommodative facility at different time points | The examination was performed before operation and 1 week, 1 month, 3 monthes, 6 monthes after ICL implantation. | Accommodative facility was measured by 3△BI/12△BO flipper. |
| Changes of phoria at different time points | The examination was performed before operation and 1 week, 1 month, 3 monthes, 6 monthes after ICL implantation. | Phoria was measured by phoropter. |
| Changes of AC/A at different time points | The examination was performed before operation and 1 week, 1 month, 3 monthes, 6 monthes after ICL implantation. | Gradient AC/A was measured by phoropter. |
| Changes of fusion vergence at different time points | The examination was performed before operation and 1 week, 1 month, 3 monthes, 6 monthes after ICL implantation. | Fusion vergence was measured by phoropter. |
| Changes of accommodative response at different time points | The examination was performed before operation and 1 week, 1 month, 3 monthes, 6 monthes after ICL implantation. | Accommodative response was measured using monocular estimated method. |
| Changes of relative accommodation at different time points | The examination was performed before operation and 1 week, 1 month, 3 monthes, 6 monthes after ICL implantation. | Relative accommodation was measured by phoropter. |
| Changes of near point of convergence at different time points | The examination was performed before operation and 1 week, 1 month, 3 monthes, 6 monthes after ICL implantation. | Near point of convergence was measured using push-up method. |
| Changes of accommodation amplitude at different time points | The examination was performed before operation and 1 week, 1 month, 3 monthes, 6 monthes after ICL implantation. | Accommodative amplitude was measured using push-up method. |
| Changes of vergence facility at different time points | The examination was performed before operation and 1 week, 1 month, 3 monthes, 6 monthes after ICL implantation. | Vergence facility was measured by +2.00D/-2.00D flipper. |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Changes of brain activation at different time points | The examination was performed before operation and 1 month, 6 monthes after ICL implantation. | Functional magnetic resonance imaging activation of the brain |
Countries
China
Contacts
Primary ContactYehong Zhuo, doctor
Backup ContactJunxiong Lin, Master
Outcome results
None listed