Embolization, Pelvic Tumor
Conditions
Brief summary
The main purpose of this study is to assess the efficacy of precision preoperative embolization in decreasing operative blood loss, reducing surgical complications in pelvic tumor surgery. Furthermore the study aims at describing the vascularity in a series of pelvic tumors, and to correlate this with perioperative blood loss.
Detailed description
The main purpose of this study is to assess the efficacy of precision preoperative embolization in decreasing operative blood loss, reducing surgical complications in pelvic tumor surgery，which including poor wound healing，nerve injury，and pelvic organs dysfunction. Furthermore the study aims at describing the vascularity in a series of pelvic tumors,which contains four grade：poor，moderate，rich and abundant and to correlate this with perioperative blood loss.
Interventions
PROCEDUREArteriography and precision preoperative embolization
Arteriography and transcatheter arterial embolization of pelvic tumors 0-24 hours prior to surgery.
PROCEDUREArteriography
Arteriography of pelvic tumors 0-24 hours prior to surgery.
Sponsors
Peking University People's Hospital
Study design
Allocation
NON_RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
SINGLE (Investigator)
Eligibility
Sex/Gender
ALL
Age
18 Years to 70 Years
Healthy volunteers
No
Inclusion criteria
* Primary or metastatic pelvic tumor * Confirmed by contrast-enhanced magnetic resonance imaging (MRI) or computed tomography (CT) of the pelvic * Planned surgical resection
Exclusion criteria
* Contrast medium allergy * Uncontrolled or concurrent illness including, but not limited to, ongoing or active infection, symptomatic congestive heart failure, unstable angina pectoris, cardiac arrhythmia, or psychiatric illness/social situations that would limit compliance with study requirements
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Perioperative blood loss | Measured intraoperatively | Perioperative blood loss measured intraoperatively |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Adverse events related to angiography or embolization | Within 2 postoperative days | Including symptoms of nerve compression, pelvic organ ischemia injury |
| Adverse events related to surgery | Within 30 postoperative days | including poor wound healing，nerve injury，pelvic organ dysfunction |
| Vascularization grade of pelvic tumors | At the angiographic procedure prior to embolization performed 0-24 hours before surgery | it contains four grades：poor、moderate、rich、abundant |
| postoperative blood loss | Within 2 postoperative days | blood loss measured through the drainage within 2 postoperative days |
Contacts
Primary ContactXIN ZHI
Backup ContactPING YIN
Outcome results
None listed