Postoperative Nausea, Vomiting
Conditions
Keywords
postoperative nausea and vomiting, laparoscopic surgery
Brief summary
The goal of this clinical trial is to compare frequency with postoperative nausea and vomiting in ASA( American Society of Anesthesiologists) I, II patients undergoing laparoscopic surgery. The main question\[s\] it aims to answer are: * Primary Outcome is the incidence of nausea and vomiting between 0-6 and 6-24 hours postoperatively and the need for additional antiemetics * Secondary outcome is detection of additional analgesic needs and complications between 0-6 and 6-24 hours postoperatively. Participants will receive aprepitant or granisetron for prevention of postoperative nausea and vomiting.
Detailed description
The aim of this study is to investigate the effectiveness of drugs used for postoperative nausea and vomiting in laparoscopic surgeries. In the research; During the operation, the patient's vitals will be recorded intraoperative forms. Vitals are; heart rate, blood pressure, oxygen saturation, end tidal carbon dioxide levels; according to the pain level after awakening from the patient follow-up forms in the service. The doses and times of analgesics will be screened, the frequencies of postoperative nausea, retching, vomiting, and additional antiemetic doses will be screened, respiratory depression, complications of anesthesia, arrhythmia, laryngospasm, hypo-hypertension, headache, dizziness, allergic reactions anxiety symptoms will be screened too. we will try to emphasize which antiemetic is more effective than the other and which one has few side effects
Interventions
The drug is given 1 hour before the start of the surgery
The drug is given 10 minutes before the patients's extubation
Sponsors
Study design
Intervention model description
group 1:patient who receive aprepitant group 2: patient who receive granisetron
Eligibility
Inclusion criteria
* ASA I, II patients patients undergoing laparoscopic surgery
Exclusion criteria
* ASA III and above patients who refused to participate in the study
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| incidence of nausea | postoperative 24 hours | the incidence of nausea between 0-6 and 6-24 hours postoperatively |
| the need for additional antiemetics | postoperative 24 hours | the need for additional antiemetics between 0-6 and 6-24 hours postoperatively |
| incidence of vomiting | postoperative 24 hours | the incidence of vomiting between 0-6 and 6-24 hours postoperatively |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| additional analgesic need | postoperative 24 hours | Detection of additional analgesic needs between 0-6 and 6-24 hours postoperatively. |
| detection of complications | postoperative 24 hours | detection of complications between 0-6 and 6-24 hours postoperatively. |
Countries
Turkey (Türkiye)