Gestational Diabetes
Conditions
Brief summary
The goal of this observational study is to compare miRNA and FGF21 in pregnancy with and without GDM (Gestational Diabetes) The main question it aims to answer that miRNA and FGF21 are different between two groups. Participants will be retrieved blood sample during first trimester and undergone 100 gm OGTT (oral glucose challenge test) during 24-28 weeks of gestation.
Detailed description
Pregnant women who attended antenatal care at Maharaj Nakorn Chiang Mai hospital during first trimester were recruited. Participants received routine standard prenatal care except, 1. additional blood test during 11-13 week 6 days (Blood was collected for further analysis) 2. performed 75gm OGTT during 24-28 week Baseline data and pregnancy outcome were reviewed.
Interventions
OTHERblood draw
Blood test for miRNA and FGF21. However, the laboratory result is not reported and not involved in management
Sponsors
Chiang Mai University
Study design
Observational model
CASE_CONTROL
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
FEMALE
Age
No minimum to 45 Years
Healthy volunteers
Yes
Inclusion criteria
* singleton pregnant women who attend at our clinic in first trimester
Exclusion criteria
* known underlying disease such as chronic hypertension, pregestational diabetes, SLE * normal structural fetal anatomical screening * incomplete obstetric data
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| miRNA profile | within 1 month after blood drawn | miRNA profile in first trimester of pregnancy and efficacy for GDM prediction |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| FGF21 profile | 6 months after blood drawn | FGF21 profile in first trimester of pregnancy and efficacy for GDM prediction |
Countries
Thailand
Outcome results
None listed