Systemic Lupus Erythematosus, PreDiabetes
Conditions
Brief summary
glucose hemosatasis, oxidative stress, abnormalities of blood pressures, and high inflammatory status is high presented in lupus patients.
Detailed description
64 lupus prediabetic women will equally distributed to group A (n =32 that will receive laser acupuncture (active) for one month (3 days week) on acupoint number 14 of GV meridian, acupoint number 4 and 11 of large intestine, acupoint number 34 of gall bladder meridian, acupoint number 3 of liver meridian, acupoint number 4, 12, and 9 of conception vessel meridian, acupoint number 40, 36, and 25 of stomach meridian, acupoint number 6 of spleen meridian, and acupoint number 5 of triple energizer meridian, laser will be applied for 1 min on every acupiont) or group B (n =32 this group will receive the same protocol of group A but the points will be sham points)
Interventions
DEVICEactive laser
32 lupus prediabetic women will receive laser acupuncture (active laser) for one month (3 days week) on acupoint number 14 of GV meridian, acupoint number 4 and 11 of large intestine, acupoint number 34 of gall bladder meridian, acupoint number 3 of liver meridian, acupoint number 4, 12, and 9 of conception vessel meridian, acupoint number 40, 36, and 25 of stomach meridian, acupoint number 6 of spleen meridian, and acupoint number 5 of triple energizer meridian, laser will be applied for 1 min on every acupiont)
DEVICEsham laser
32 lupus prediabetic women will receive laser acupuncture (sham laser, i.e power of device will be zero watt) for one month (3 days week) on acupoint number 14 of GV meridian, acupoint number 4 and 11 of large intestine, acupoint number 34 of gall bladder meridian, acupoint number 3 of liver meridian, acupoint number 4, 12, and 9 of conception vessel meridian, acupoint number 40, 36, and 25 of stomach meridian, acupoint number 6 of spleen meridian, and acupoint number 5 of triple energizer meridian, laser will be applied for 1 min on every acupiont)
Sponsors
Cairo University
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
SINGLE (Outcomes Assessor)
Eligibility
Sex/Gender
FEMALE
Age
18 Years to 50 Years
Healthy volunteers
No
Inclusion criteria
* prediabetic lupus females (n =64)
Exclusion criteria
* obesity diabetes heart or respiratory problems
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Malondialdehyde | It will be measured after 4 weeks of laser application | oxidative stress indicator |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| diastolic blood pressure | It will be measured after 4 weeks of laser application | manual sphygmomanometer |
| blood glucose | It will be measured after 4 weeks of laser application | it will be measured in fasting status |
| erythrocyte sedimentation rate (at first hour) | It will be measured after 4 weeks of laser application | it will be measured in serum |
| erythrocyte sedimentation rate (at second hour) | It will be measured after 4 weeks of laser application | it will be measured in serum |
| systolic blood pressure | It will be measured after 4 weeks of laser application | manual sphygmomanometer |
| adenosine triphosphate | It will be measured after 4 weeks of laser application | it a measure for energy production |
| Nitrate | It will be measured after 4 weeks of laser application | it will be measured in serum |
| Glutathione | It will be measured after 4 weeks of laser application | it will be measured in serum |
| C reactive protein | It will be measured after 4 weeks of laser application | it will be measured in serum |
Countries
Egypt
Contacts
Primary ContactAli Ismail, lecturer
Outcome results
None listed