Oocyte Retrieval
Conditions
Brief summary
In this study; during the oocyte retrieval procedure, it was aimed to compare two different general anesthesia methods, in which propofol was administered as infusion according to the patient's Bispectral index system (BIS) value or in bolus doses according to the patient's clinic.The hypothesis of the study; during the oocyte retrieval process, when propofol is administered as an infusion and accompanied by BIS monitoring, adequate anesthesia level will be achieved with less amount of bolus doses according to the clinical condition of the patient.
Detailed description
130 patients over the age of 18, ASA I-II, who underwent oocyte retrieval for IVF treatment were included in the study. The patients divided into two groups. In induction, 2mg/kg fentanyl, 40mg lidocaine and 2mg/kg propofol administered to all patients. Patients in group 1; propofol added in bolus doses of 0.5mg/kg. Doses determined according to the clinical condition of the patient. Patients in group 2; propofol administered as 10mg/kg/hour infusion. The infusion dose adjusted so that the Bispectral index (BIS) is in the range of 40-60.
Interventions
DRUGpropofol bolus
Propofol will be added in bolus doses of 0.5mg/kg.
Propofol will be administered as 10mg/kg/hour infusion.
Sponsors
Acibadem University
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
HEALTH_SERVICES_RESEARCH
Masking
DOUBLE (Subject, Investigator)
Eligibility
Sex/Gender
FEMALE
Age
18 Years to No maximum
Healthy volunteers
Yes
Inclusion criteria
* Over 18 years * ASA I-II * Patients who underwent oocyte retrieval for IVF treatment
Exclusion criteria
1. The patient does not want to participate 2. ASA \> II patients 3. Patients under 18 years of age 4. Patients who are allergic to the drugs used 5. Patients with mental illness 6. Patients with alcohol or substance addiction
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Propofol | up to 1 hour | The total amount of Propofol (mg) administered during the procedure |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Observer's assessment of sedation scale (OSS) | up to 1 hour | Time to reach 5 on the observer's assessment of sedation scale of the patients |
| (Post Anesthetic Discharge Scoring System) PADSS | up to 6 hour | Time of patients to reach PADSS ≥ 9 (Min:0 and Max: 10) PADSS ≥ 9 is suitable for discharge of the patient |
| (Satisfaction of patients) STF 1 | up to 6 hour | Patient satisfaction (The scale is in the range of 1-4. 1: the best) |
| (Satisfaction of gynecologist) STF 2 | up to 1 hour | Satisfaction of the doctor performing the procedure(The scale is in the range of 1-4. 1: the best) |
Countries
Turkey (Türkiye)
Outcome results
None listed