Autoimmune Epilepsy, Healthy
Conditions
Brief summary
The purpose of this research is to search for reproducible changes in a wide range of physical signals, including heart rate, muscle tone and activity and EEG before and at the onset of seizures in patients with epilepsy.
Interventions
DEVICEBiosensor
Noninvasive wearable biosensor device worn on the primary affected wrist or upper arm for as much time as is feasible for 7-10 days
Sponsors
Mayo Clinic
Study design
Allocation
NON_RANDOMIZED
Intervention model
PARALLEL
Primary purpose
BASIC_SCIENCE
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
18 Years to 70 Years
Healthy volunteers
Yes
Inclusion criteria
* Patients diagnosed with or suspected of having autoimmune epilepsy. * Normal controls - cognitively normal subjects without epilepsy
Exclusion criteria
• Cognitive or psychiatric condition rendering patient unable to cooperate with data collection or manage and recharge smart watch and tablet computer devices. Presence of open or healing wounds near monitoring sites (infection risk).
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Number of high-quality physiological signals | 10 days | Total number of high-quality physiological signals recorded by biosensors |
| Number of Reproducible changes in physiological biosignals | 10 days | Identification of reproducible changes in one or more physiological biosignals at onset of video and/or EEG-identified seizures |
Countries
United States
Outcome results
None listed