Biomarker-s of Abusive Head Trauma by Proteomics

Identification of Novel Biomarker-s of Abusive Head Trauma on Serum by Proteomics

Status

Not yet recruiting

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT05626465

Enrollment

174

Registered

2022-11-23

Start date

2023-02-28

Completion date

2028-02-29

Last updated

2023-01-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Abuse, Child, Protein Disorder, Blood

Keywords

abusive head trauma, proteomic, biomarker

Brief summary

The aim of our study is to highlight biomarker-s of Abusive Head Trauma by proteomics analyses on the serum of child victims of abuse.

Interventions

OTHERBlood test

Proteomic analyses on serum

Study design

Observational model

CASE_CONTROL

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

No minimum to 2 Years

Healthy volunteers

Yes

Inclusion criteria

* Age : 0-2 y.o * Medical consultation for malaise, seizure (without fever), loss of consciousness, traumatic bain injury, or cranioplasty * Blood test during medical care * Accepted informed consent

Exclusion criteria

* Refused informed consent * For control groups : medical history of child abuse * For AHT group : rare metabolic disease (Menkes, etc..)

Design outcomes

Primary

Measure	Time frame	Description
Highlight novel biomarker-s of AHT	Hospital admission to discharge (up to 3 days)	Proteomic analyses will be made on serum of infant victim of AHT. Results will be compare with control groups (traumatic brain injury, cranioplasty, malaise).

Countries

France, Switzerland

Contacts

Primary ContactKim Wiskott, MD

kim.wiskott@hcuge.ch0041797737424

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026